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Mark E Cooper

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Articles 385
Citations 18699
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Recent Articles
1.
Huynh P, Yang Y, Tian H, Wu T, Huang M, Tang J, et al.
Int J Mol Sci . 2025 Mar; 26(5). PMID: 40076647
Cell Division Autoantigen 1 (CDA1) has been shown to play a role in enhancing transforming growth factor beta (TGFβ) signaling, leading to fibrosis in diabetic kidney disease (DKD) using mouse...
2.
Liu K, Cooper M, Chai Z, Liu F
Int J Mol Sci . 2025 Feb; 26(4). PMID: 40004147
High-density lipoprotein (HDL) exhibits multiple metabolic protective functions, such as facilitating cellular cholesterol efflux, antioxidant, anti-inflammatory, anti-apoptotic and anti-thrombotic properties, showing antidiabetic and renoprotective potential. Diabetic kidney disease (DKD) is...
3.
Zou Y, Yang Q, Lang Y, Liu K, Yuan J, Yang J, et al.
Diabetes Obes Metab . 2024 Nov; 27(2):629-641. PMID: 39568393
Background: The Stress Hyperglycemia Ratio (SHR), a new biomarker calculated from glucose and HbA1c levels, has been linked to significant clinical outcomes in diabetes. This study investigates the potential of...
4.
Fu T, Mohan M, Bose M, Brennan E, Kiriazis H, Deo M, et al.
Cardiovasc Diabetol . 2024 Nov; 23(1):413. PMID: 39563316
Background: Diabetic heart disease may eventually lead to heart failure, a leading cause of mortality in diabetic individuals. The lack of effective treatments for diabetes-induced heart failure may result from...
5.
Adeshara K, Di Marco E, Bordino M, Gordin D, Bernardi L, Cooper M, et al.
Cardiovasc Diabetol . 2024 Sep; 23(1):350. PMID: 39342285
Background: Hyperglycemia-induced oxidative stress is a well-established pathological mediator of vascular complications in diabetes. We assessed plasma oxidant and antioxidant levels in response to acute and chronic hyperglycemia in relation...
6.
Wei Y, Mou S, Yang Q, Liu F, Cooper M, Chai Z
Clin Sci (Lond) . 2024 Aug; 138(16):991-1007. PMID: 39139135
Cellular senescence represents a condition of irreversible cell cycle arrest, characterized by heightened senescence-associated beta-galactosidase (SA-β-Gal) activity, senescence-associated secretory phenotype (SASP), and activation of the DNA damage response (DDR). Diabetic...
7.
Thomas M, Cooper M
Nat Rev Nephrol . 2024 Jul; 20(10):637-638. PMID: 39075285
No abstract available.
8.
Khan A, Aziz M, Sourris K, Lee M, Dai A, Watson A, et al.
Diabetes . 2024 Jun; 73(9):1495-1512. PMID: 38905153
Article Highlights:
9.
Bonnet F, Cooper M, Kopp L, Fouque D, Candido R
Diabetes Obes Metab . 2024 Jun; 26 Suppl 6:55-65. PMID: 38899425
Diabetic nephropathy, also known as diabetic kidney disease (DKD), remains a challenge in clinical practice as this is the major cause of kidney failure worldwide. Clinical trials do not answer...
10.
Jandeleit-Dahm K, Kankanamalage H, Dai A, Meister J, Lopez-Trevino S, Cooper M, et al.
Antioxidants (Basel) . 2024 Apr; 13(4). PMID: 38671844
Chronic hyperglycemia induces intrarenal oxidative stress due to the excessive production of reactive oxygen species (ROS), leading to a cascade of events that contribute to the development and progression of...