Miranda L Jacobs
Overview
Explore the profile of Miranda L Jacobs including associated specialties, affiliations and a list of published articles.
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9
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105
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Recent Articles
1.
Steinkuhler J, Peruzzi J, Kruger A, Villasenor C, Jacobs M, Jewett M, et al.
ACS Synth Biol
. 2023 Dec;
13(1):129-140.
PMID: 38150067
Cell-free gene expression (CFE) systems are powerful tools for transcribing and translating genes outside of a living cell. Synthesis of membrane proteins is of particular interest, but their yield in...
2.
Manzer Z, Ghosh S, Roy A, Jacobs M, Carten J, Kamat N, et al.
ACS Synth Biol
. 2023 Jan;
12(2):502-510.
PMID: 36651574
Assembling transmembrane proteins on organic electronic materials is one promising approach to couple biological functions to electrical readouts. A biosensing device produced in such a way would enable both the...
3.
Steinkuhler J, Jacobs M, Boyd M, Villasenor C, Loverde S, Kamat N
Biomacromolecules
. 2022 Nov;
23(11):4756-4765.
PMID: 36318160
Hybrid membranes assembled from biological lipids and synthetic polymers are a promising scaffold for the reconstitution and utilization of membrane proteins. Recent observations indicate that inclusion of small fractions of...
4.
Manzer Z, Ghosh S, Jacobs M, Krishnan S, Zipfel W, Pineros M, et al.
ACS Appl Bio Mater
. 2022 Jan;
4(4):3101-3112.
PMID: 35014398
Supported lipid bilayers (SLBs) hold tremendous promise as cellular-mimetic structures that can be readily interfaced with analytical and screening tools. The incorporation of transmembrane proteins, a key component in biological...
5.
Jacobs M, Kamat N
Methods Mol Biol
. 2022 Jan;
2433:257-271.
PMID: 34985750
Hybrid membranes comprised of diblock copolymers, and phospholipids have gained interest due to their unique properties that result from blending natural and synthetic components. The integration of membrane proteins into...
6.
Jacobs M, Faizi H, Peruzzi J, Vlahovska P, Kamat N
Biophys J
. 2021 Apr;
120(11):2317-2329.
PMID: 33887229
Polyunsaturated fatty acids (PUFAs) modify the activity of a wide range of membrane proteins and are increasingly hypothesized to modulate protein activity by indirectly altering membrane physical properties. Among the...
7.
Peruzzi J, Jacobs M, Vu T, Wang K, Kamat N
Angew Chem Int Ed Engl
. 2019 Oct;
58(51):18683-18690.
PMID: 31596992
Targeted vesicle fusion is a promising approach to selectively control interactions between vesicle compartments and would enable the initiation of biological reactions in complex aqueous environments. Here, we explore how...
8.
Hilburger C, Jacobs M, Lewis K, Peruzzi J, Kamat N
ACS Synth Biol
. 2019 May;
8(6):1224-1230.
PMID: 31051071
The assembly of channel proteins into vesicle membranes is a useful strategy to control activities of vesicle-based systems. Here, we developed a membrane AND gate that responds to both a...
9.
Jacobs M, Boyd M, Kamat N
Proc Natl Acad Sci U S A
. 2019 Feb;
116(10):4031-4036.
PMID: 30760590
The expression and integration of membrane proteins into vesicle membranes is a critical step in the design of cell-mimetic biosensors, bioreactors, and artificial cells. While membrane proteins have been integrated...