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Jung Ae Kang

Explore the profile of Jung Ae Kang including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 88
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Recent Articles
1.
Ryu Y, Kang J, Kim D, Kim S, Kim S, Park S, et al.
Small . 2018 Nov; 14(52):e1802618. PMID: 30398698
With a growing number of intracellular drug targets and the high efficacy of protein therapeutics, the targeted delivery of active proteins with negligible toxicity is a challenging issue in the...
2.
Kang J, Yoon S, Rho J, Jang B, Choi D, Lee D, et al.
Food Sci Biotechnol . 2018 Sep; 25(Suppl 1):163-168. PMID: 30263502
This study was conducted to evaluate the preventive effect of hesperetin against radiation-induced DNA damage and immune dysfunction in murine splenocytes. Isolated splenocytes from BALB/c mice were treated with hesperetin...
3.
Mushtaq S, Nam Y, Kang J, Choi D, Park S
ACS Omega . 2018 Jul; 3(6):6903-6911. PMID: 30023965
In this report, the novel and site-specific radioiodination of biomolecules by using aryl diamine and alkyl aldehyde condensation reaction in the presence of a Cu catalyst under ambient conditions was...
4.
Kim T, Seo H, Lee J, Kang J, Kim W, Kim H, et al.
J Control Release . 2018 Apr; 279:282-291. PMID: 29698702
Small-sized non-antibody scaffolds have attracted considerable interest as alternatives to immunoglobulin antibodies. However, their short half-life is considered a drawback in the development of therapeutic agents. Here we demonstrate that...
5.
Kang J, Song H, Byun E, Ahn N, Kim H, Nam Y, et al.
Food Chem Toxicol . 2017 Nov; 111:133-143. PMID: 29126802
Gamma irradiation is able to affect various structural modification and an increase of the biological properties of biomaterials. This study was conducted to investigate the anti-allergenic effect of γ-irradiated black...
6.
Mushtaq S, Rho J, Kang J, Lee J, Kim J, Nam Y, et al.
Bioorg Med Chem Lett . 2017 Oct; 27(22):5060-5064. PMID: 29042166
Antibody-mimetic proteins are intensively being developed for biomedical applications including tumor imaging and therapy. Among them, repebody is a new class of protein that consists of highly diverse leucine-rich repeat...
7.
Kim H, Kang J, Ryou J, Lee G, Choi D, Lee D, et al.
ACS Chem Biol . 2017 Oct; 12(11):2891-2897. PMID: 29019389
With the high efficacy of protein-based therapeutics and plenty of intracellular drug targets, cytosolic protein delivery in a cell-specific manner has attracted considerable attention in the field of precision medicine....
8.
Byun E, Song H, Mushtaq S, Kim H, Kang J, Yang M, et al.
J Med Food . 2017 Jul; 20(8):812-819. PMID: 28753056
Luteolin was gamma irradiated at doses of 0, 15, 30, 50, 70, and 100 kGy. We observed that the luteolin peak decreased simultaneously with the appearance of new radiolytic peaks,...
9.
Lee J, Kang J, Ryu Y, Han S, Nam Y, Rho J, et al.
Biomaterials . 2016 Dec; 120:22-31. PMID: 28024232
The integration of a targeted delivery with a tumour-selective agent has been considered an ideal platform for achieving high therapeutic efficacy and negligible side effects in cancer therapy. Here, we...
10.
Choi M, Shim H, Nam Y, Kim H, Kang J, Lee D, et al.
Bioorg Med Chem Lett . 2016 Jan; 26(3):875-878. PMID: 26748695
Herein we report the radiosynthesis of a pyridine derived azide prosthetic group for iodine radioisotope labeling of dibenzocyclooctyne (DBCO) conjugated molecules. The radiolabeling of the stannylated precursor 2 was conducted...