Jun-Ichi Sakamaki
Overview
Explore the profile of Jun-Ichi Sakamaki including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
1938
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Recent Articles
21.
Sakamaki J, Fu A, Reeks C, Baird S, Depatie C, Al Azzabi M, et al.
Nat Cell Biol
. 2014 Feb;
16(3):234-44.
PMID: 24561619
Energy sensing by the AMP-activated protein kinase (AMPK) is of fundamental importance in cell biology. In the pancreatic β-cell, AMPK is a central regulator of insulin secretion. The capacity of...
22.
Sakamaki J, Daitoku H, Kaneko Y, Hagiwara A, Ueno K, Fukamizu A
J Recept Signal Transduct Res
. 2012 Mar;
32(2):96-101.
PMID: 22384829
Hepatic gluconeogenesis is important for the maintenance of blood glucose homeostasis under fasting condition. Hepatocyte nuclear factor 4α (HNF4α) and FOXO1 transcription factors have implicated in this process through transcriptional...
23.
Sakamaki J, Daitoku H, Ueno K, Hagiwara A, Yamagata K, Fukamizu A
Proc Natl Acad Sci U S A
. 2011 Mar;
108(15):6085-90.
PMID: 21444773
Protein arginine methylation is a common posttranslational modification catalyzed by a family of the protein arginine methyltransferases (PRMTs). We have previously reported that PRMT1 methylates Forkhead box O transcription factors...
24.
Daitoku H, Sakamaki J, Fukamizu A
Biochim Biophys Acta
. 2011 Mar;
1813(11):1954-60.
PMID: 21396404
The forkhead box O transcription factors convert a variety of external stimuli, including growth factors, nutrients, and oxidative stress, into diverse biological responses through modulation of specific gene expression. Forkhead...
25.
Sakamaki J, Daitoku H, Yoshimochi K, Miwa M, Fukamizu A
Biochem Biophys Res Commun
. 2009 Mar;
382(3):497-502.
PMID: 19281796
Forkhead box O (FOXO) transcription factors play an important role in a wide range of biological processes, including cell cycle control, apoptosis, detoxification of reactive oxygen species, and gluconeogenesis through...
26.
Hirota K, Sakamaki J, Ishida J, Shimamoto Y, Nishihara S, Kodama N, et al.
J Biol Chem
. 2008 Sep;
283(47):32432-41.
PMID: 18805788
Glucokinase (GK) and glucose-6-phosphatase (G6Pase) regulate rate-limiting reactions in the physiologically opposed metabolic cascades, glycolysis and gluconeogenesis, respectively. Expression of these genes is conversely regulated in the liver in response...