Tim Van Acker
Overview
Explore the profile of Tim Van Acker including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
442
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Van Acker T, Tavernier J, Peelman F
Int J Mol Sci
. 2019 May;
20(9).
PMID: 31060328
The small GTase Arf6 has several important functions in intracellular vesicular trafficking and regulates the recycling of different types of cargo internalized via clathrin-dependent or -independent endocytosis. It activates the...
2.
New M, Van Acker T, Sakamaki J, Jiang M, Saunders R, Long J, et al.
Cancer Res
. 2019 Feb;
79(8):1884-1898.
PMID: 30765601
Pancreatic ductal adenocarcinoma (PDAC) is driven by metabolic changes in pancreatic cells caused by oncogenic mutations and dysregulation of p53. PDAC cell lines and PDAC-derived xenografts grow as a result...
3.
New M, Van Acker T, Jiang M, Saunders R, Long J, Sakamaki J, et al.
Methods Mol Biol
. 2019 Jan;
1880:359-374.
PMID: 30610710
Autophagy is a highly regulated process, and its deregulation can contribute to various diseases, including cancer, immune diseases, and neurodegenerative disorders. Here we describe the design, protocol, and analysis of...
4.
Sakamaki J, Long J, New M, Van Acker T, Tooze S, Ryan K
Transcription
. 2017 Oct;
9(2):131-136.
PMID: 28980873
Autophagy is an essential cellular process that degrades cytoplasmic organelles and components. Precise control of autophagic activity is achieved by context-dependent signaling pathways. Recent studies have highlighted the involvement of...
5.
Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, OPrey J, Clark W, et al.
Mol Cell
. 2017 May;
66(4):517-532.e9.
PMID: 28525743
Autophagy is a membrane-trafficking process that directs degradation of cytoplasmic material in lysosomes. The process promotes cellular fidelity, and while the core machinery of autophagy is known, the mechanisms that...
6.
New M, Van Acker T, Long J, Sakamaki J, Ryan K, Tooze S
Front Oncol
. 2017 Mar;
7:28.
PMID: 28316954
Pancreatic ductal adenocarcinoma (PDAC) is one of the few cancer types where the 5-year survival rate shows no improvement. Despite conflicting evidence, the majority of data points to an essential...
7.
Vyncke L, Bovijn C, Pauwels E, Van Acker T, Ruyssinck E, Burg E, et al.
Structure
. 2016 Feb;
24(3):437-47.
PMID: 26876098
Members of the Toll-like receptor and interleukin-1 (IL-1) receptor families all signal via Toll/IL-1R (TIR) domain-driven assemblies with adaptors such as MyD88. We here combine the mammalian two-hybrid system MAPPIT...
8.
Van Acker T, Eyckerman S, Vande Walle L, Gerlo S, Goethals M, Lamkanfi M, et al.
J Biol Chem
. 2013 Dec;
289(3):1364-76.
PMID: 24297182
Recognition of lipopolysaccharides (LPS) by Toll-like receptor 4 (TLR4) at the plasma membrane triggers NF-κB activation through recruitment of the adaptor proteins Mal and MyD88. Endocytosis of the activated TLR4...
9.
Bustin S, Benes V, Garson J, Hellemans J, Huggett J, Kubista M, et al.
Nat Methods
. 2013 Nov;
10(11):1063-7.
PMID: 24173381
Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of essential technical information. Reporting standards are significantly improved...
10.
Bovijn C, Desmet A, Uyttendaele I, Van Acker T, Tavernier J, Peelman F
J Biol Chem
. 2013 Mar;
288(17):12054-66.
PMID: 23460645
Upon activation, Toll-like receptor 4 (TLR4) binds adapter proteins, including MyD88 (myeloid differentiation primary response gene 88) and Mal (MyD88 adapter-like) for its signal transduction. TLR4 and the adapter proteins...