Juan Cabello
Overview
Explore the profile of Juan Cabello including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
770
Followers
0
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Recent Articles
1.
Romero-Aranda C, Saenz-Narciso B, Gomez-Orte E, Metola A, Ezcurra B, Calvo O, et al.
MicroPubl Biol
. 2024 Nov;
2024.
PMID: 39575199
The Integrator complex is a set of at least 13 evolutionarily conserved proteins that binds the C-terminal domain of RNA polymerase II to regulate snRNA 3'-end processing and gene expression....
2.
Guijarro-Hernandez A, Hurtado C, Urizar-Compains E, Ezcurra B, Galiana-Saenz A, Baquero E, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39519157
In previous research, we created a model with homozygous mutations in calreticulin similar to those found in patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF), two myeloproliferative neoplasms (MPNs)....
3.
Colino-Lage H, Guerrero-Gomez D, Gomez-Orte E, Gonzalez X, Martina J, Dansen T, et al.
Free Radic Biol Med
. 2024 Jul;
223:369-383.
PMID: 39059513
Basic Helix-Loop-Helix (bHLH) transcription factors TFEB/TFE3 and HLH-30 are key regulators of autophagy induction and lysosomal biogenesis in mammals and C. elegans, respectively. While much is known about the regulation...
4.
Escrich V, Romero-Aranda C, Lopez R, de Toro M, Metola A, Ezcurra B, et al.
Cancers (Basel)
. 2024 Jul;
16(13).
PMID: 39001402
The human Integrator complex is a set of 15 subunits that mediates processing of small nuclear RNAs (snRNAs), and which later participates in splicing messenger RNAs (mRNAs). In addition, it...
5.
Guijarro-Hernandez A, Eder-Azanza L, Hurtado C, Navarro-Herrera D, Ezcurra B, Novo F, et al.
Cells
. 2023 Jan;
12(1).
PMID: 36611979
There is growing evidence that -negative myeloproliferative neoplasms (MPNs) are disorders in which multiple molecular mechanisms are significantly disturbed. Since their discovery, driver mutations have been demonstrated to trigger pathogenic...
6.
Blanco-Luquin I, Acha B, Urdanoz-Casado A, Gomez-Orte E, Roldan M, Perez-Rodriguez D, et al.
Cells
. 2022 Apr;
11(7).
PMID: 35406633
In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis model to recapitulate DNA methylation marks in the...
7.
Garcia-Casas P, Alvarez-Illera P, Gomez-Orte E, Cabello J, Fonteriz R, Montero M, et al.
Front Pharmacol
. 2021 Jul;
12:695687.
PMID: 34211399
We have reported recently that the mitochondrial Na/Ca exchanger inhibitor CGP37157 extends lifespan in by a mechanism involving mitochondria, the TOR pathway and the insulin/IGF1 pathway. Here we show that...
8.
Martina J, Guerrero-Gomez D, Gomez-Orte E, Barcena J, Cabello J, Miranda-Vizuete A, et al.
EMBO J
. 2020 Dec;
40(3):e105793.
PMID: 33314217
Mammalian TFEB and TFE3, as well as their ortholog in Caenorhabditis elegans HLH-30, play an important role in mediating cellular response to a variety of stress conditions, including nutrient deprivation,...
9.
Escrich V, Ezcurra B, Gomez-Orte E, Romero-Aranda C, Miranda-Vizuete A, Cabello J
J Vis Exp
. 2020 Oct;
(164).
PMID: 33104066
4D microscopy is an invaluable tool for unraveling the embryonic developmental process in different animals. Over the last decades, Caenorhabditis elegans has emerged as one of the best models for...
10.
Zheleva A, Gomez-Orte E, Saenz-Narciso B, Ezcurra B, Kassahun H, de Toro M, et al.
PLoS Genet
. 2019 Sep;
15(9):e1008338.
PMID: 31525188
Animal development requires the execution of specific transcriptional programs in different sets of cells to build tissues and functional organs. Transcripts are exported from the nucleus to the cytoplasm where...