Beatriz Saenz-Narciso
Overview
Explore the profile of Beatriz Saenz-Narciso including associated specialties, affiliations and a list of published articles.
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11
Citations
174
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Recent Articles
1.
Romero-Aranda C, Saenz-Narciso B, Gomez-Orte E, Metola A, Ezcurra B, Calvo O, et al.
MicroPubl Biol
. 2024 Nov;
2024.
PMID: 39575199
The Integrator complex is a set of at least 13 evolutionarily conserved proteins that binds the C-terminal domain of RNA polymerase II to regulate snRNA 3'-end processing and gene expression....
2.
Matheson L, Petkau G, Saenz-Narciso B, DAngeli V, McHugh J, Newman R, et al.
Sci Rep
. 2022 Nov;
12(1):19657.
PMID: 36385275
The ZFP36 family of RNA-binding proteins acts post-transcriptionally to repress translation and promote RNA decay. Studies of genes and pathways regulated by the ZFP36 family in CD4 T cells have...
3.
Zheleva A, Gomez-Orte E, Saenz-Narciso B, Ezcurra B, Kassahun H, de Toro M, et al.
PLoS Genet
. 2019 Sep;
15(9):e1008338.
PMID: 31525188
Animal development requires the execution of specific transcriptional programs in different sets of cells to build tissues and functional organs. Transcripts are exported from the nucleus to the cytoplasm where...
4.
Gomez-Orte E, Saenz-Narciso B, Zheleva A, Ezcurra B, de Toro M, Lopez R, et al.
PLoS Genet
. 2019 Feb;
15(2):e1007981.
PMID: 30807579
Gene expression is generally regulated by recruitment of transcription factors and RNA polymerase II (RNAP II) to specific sequences in the gene promoter region. The Integrator complex mediates processing of...
5.
Guerrero-Gomez D, Mora-Lorca J, Saenz-Narciso B, Naranjo-Galindo F, Munoz-Lobato F, Parrado-Fernandez C, et al.
Cell Death Differ
. 2019 Feb;
26(9):1545-1565.
PMID: 30770874
In the presence of aggregation-prone proteins, the cytosol and endoplasmic reticulum (ER) undergo a dramatic shift in their respective redox status, with the cytosol becoming more oxidized and the ER...
6.
Gomez-Orte E, Cornes E, Zheleva A, Saenz-Narciso B, de Toro M, Iniguez M, et al.
Oncotarget
. 2018 Mar;
9(11):9556-9571.
PMID: 29515753
The transcriptomes of model organisms have been defined under specific laboratory growth conditions. The standard protocol for growth and maintenance is 20°C on an diet. Temperatures ranging from 15°C to...
7.
Saenz-Narciso B, Gomez-Orte E, Zheleva A, Gastaca I, Cabello J
Bioessays
. 2016 Oct;
38(12):1246-1254.
PMID: 27790724
Small GTPases in the Rho family act as major nodes with functions beyond cytoskeletal rearrangements shaping the Caenorhabditis elegans embryo during development. These small GTPases are key signal transducers that...
8.
Mora-Lorca J, Saenz-Narciso B, Gaffney C, Naranjo-Galindo F, Pedrajas J, Guerrero-Gomez D, et al.
Free Radic Biol Med
. 2016 Apr;
96:446-61.
PMID: 27117030
Glutathione is the most abundant thiol in the vast majority of organisms and is maintained in its reduced form by the flavoenzyme glutathione reductase. In this work, we describe the...
9.
Saenz-Narciso B, Gomez-Orte E, Zheleva A, Torres-Perez R, Cabello J
Bioessays
. 2014 Dec;
37(3):237-9.
PMID: 25545039
Nowadays, in the Internet databases era, certain knowledge is being progressively lost. This knowledge, which we feel is essential and should be acquired through education, is the understanding of how...
10.
Sanchez-Blanco A, Rodriguez-Matellan A, Reis-Sobreiro M, Saenz-Narciso B, Cabello J, Mohler W, et al.
Cell Cycle
. 2014 Dec;
13(21):3375-89.
PMID: 25485582
Drugs capable of specifically recognizing and killing cancer cells while sparing healthy cells are of great interest in anti-cancer therapy. An example of such a drug is edelfosine, the prototype...