» Authors » Joshy George

Joshy George

Explore the profile of Joshy George including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 85
Citations 8345
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Collin L, Cushing-Haugen K, Terry K, Goode E, Wu A, Harris H, et al.
Cancer Epidemiol Biomarkers Prev . 2025 Feb; PMID: 40009771
Background: Ovarian high-grade serous carcinomas (HGSC) comprise four distinct molecular subtypes based on mRNA expression patterns, with differential survival. Understanding risk factor associations is important to elucidate the etiology of...
2.
Mills M, Emori C, Kumar P, Boucher Z, George J, Bolcun-Filas E
Dev Biol . 2024 Sep; 517:55-72. PMID: 39306223
Immature oocytes enclosed in primordial follicles stored in female ovaries are under constant threat of DNA damage induced by endogenous and exogenous factors. Checkpoint kinase 2 (CHEK2) is a key...
3.
Zhao Y, Ansarullah , Kumar P, Mahoney J, He H, Baker C, et al.
bioRxiv . 2024 Jun; PMID: 38826370
The molecular pathogenesis of diabetes is multifactorial, involving genetic predisposition and environmental factors that are not yet fully understood. However, pancreatic β-cell failure remains among the primary reasons underlying the...
4.
Suh Y, Lee J, George J, Seol D, Jeong K, Oh S, et al.
Br J Cancer . 2024 Mar; 130(9):1571-1584. PMID: 38467827
Background: Molecular analysis of advanced tumors can increase tumor heterogeneity and selection bias. We developed a robust prognostic signature for gastric cancer by comparing RNA expression between very rare early...
5.
Mills M, Emori C, Kumar P, Boucher Z, George J, Bolcun-Filas E
bioRxiv . 2024 Feb; PMID: 38352597
Immature oocytes enclosed in primordial follicles stored in female ovaries are under constant threat of DNA damage induced by endogenous and exogenous factors. Checkpoint kinase 2 (CHEK2) is a key...
6.
Toufiq M, Rinchai D, Bettacchioli E, Kabeer B, Khan T, Subba B, et al.
J Transl Med . 2023 Oct; 21(1):728. PMID: 37845713
Background: Feature selection is a critical step for translating advances afforded by systems-scale molecular profiling into actionable clinical insights. While data-driven methods are commonly utilized for selecting candidate genes, knowledge-driven...
7.
George J, Chen Y, Abdelfattah N, Yamamoto K, Gallup T, Adamson S, et al.
Cancer Res Commun . 2023 Jan; 2(6):402-416. PMID: 36688010
The emergence of treatment resistance significantly reduces the clinical utility of many effective targeted therapies. Although both genetic and epigenetic mechanisms of drug resistance have been reported, whether these mechanisms...
8.
Li Y, Chen M, George J, Liu E, Karuturi R
J Comput Biol . 2022 Nov; 30(4):376-390. PMID: 36445177
Testing and isolation of infectious employees is one of the critical strategies to make the workplace safe during the pandemic for many organizations. Adaptive testing frequency reduces cost while keeping...
9.
Posner A, Prall O, Sivakumaran T, Etemadamoghadam D, Thio N, Pattison A, et al.
J Pathol . 2022 Oct; 259(1):81-92. PMID: 36287571
Cancer of unknown primary (CUP) is a syndrome defined by clinical absence of a primary cancer after standardised investigations. Gene expression profiling (GEP) and DNA sequencing have been used to...
10.
Martinek J, Wu T, Sun L, Lin J, Kim K, Marches F, et al.
STAR Protoc . 2022 Sep; 3(4):101698. PMID: 36149794
We describe a pipeline for optimized and streamlined multiplexed immunofluorescence-guided laser capture microdissection allowing the harvest of individual cells based on their phenotype and tissue localization for transcriptomic analysis with...