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Joshua Pelta-Heller

Explore the profile of Joshua Pelta-Heller including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 145
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Recent Articles
1.
Cai J, Schleidt S, Pelta-Heller J, Hutchings D, Cannarsa G, Iacovitti L
Dev Biol . 2013 Jan; 376(1):62-73. PMID: 23352789
Although many laboratories currently use small molecule inhibitors of the BMP (Dorsomorphin/DM) and TGF-β (SB431542/SB) signaling pathways in protocols to generate midbrain dopamine (mDA) neurons from hES and hiPS cells,...
2.
Zuzga D, Pelta-Heller J, Li P, Bombonati A, Waldman S, Pitari G
Int J Cancer . 2011 Jun; 130(11):2539-48. PMID: 21702043
In colorectal cancer, the antitumorigenic guanylyl cyclase C (GCC) signalome is defective reflecting ligand deprivation from downregulation of endogenous hormone expression. Although the proximal intracellular mediators of that signal transduction...
3.
Page M, Bao L, Andre P, Pelta-Heller J, Sluzas E, Gonzalez-Alegre P, et al.
Neurobiol Dis . 2010 May; 39(3):318-26. PMID: 20460154
Early onset torsion dystonia is an autosomal dominant movement disorder of variable penetrance caused by a glutamic acid, i.e. DeltaE, deletion in DYT1, encoding the protein TorsinA. Genetic and structural...
4.
Lubbe W, Zuzga D, Zhou Z, Fu W, Pelta-Heller J, Muschel R, et al.
Cancer Res . 2009 Apr; 69(8):3529-36. PMID: 19336567
Matrix metalloproteinase-9 (MMP-9) produced by colorectal cancer cells is a critical determinant of metastatic disease progression and an attractive target for antimetastatic strategies to reduce colon cancer mortality. Cellular signaling...
5.
Bogush A, Pedrini S, Pelta-Heller J, Chan T, Yang Q, Mao Z, et al.
J Biol Chem . 2007 Jan; 282(10):7352-9. PMID: 17209049
Mature striatal medium size spiny neurons express the dopamine and cyclic AMP-regulated phosphoprotein, 32 kDa (DARPP-32), but little is known about the mechanisms regulating its levels or the specification of...