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Michelle E Ehrlich

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Articles 114
Citations 3131
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Recent Articles
1.
Castranio E, Varghese M, Argyrousi E, Tripathi K, Soderberg L, Bresnahan E, et al.
bioRxiv . 2025 Mar; PMID: 40060689
Teaser: APP "NFA-Aβ only" mice reveal clinically relevant mechanisms despite the absence of detectable inflammation.
2.
Readhead B, Mastroeni D, Wang Q, Sierra M, de Avila C, Jimoh T, et al.
Alzheimers Dement . 2024 Dec; 21(1):e14401. PMID: 39698934
Introduction: While there may be microbial contributions to Alzheimer's disease (AD), findings have been inconclusive. We recently reported an AD-associated CD83(+) microglia subtype associated with increased immunoglobulin G4 (IgG4) in...
3.
Perez Garcia G, Bicak M, Buros J, Haure-Mirande J, Perez G, Otero-Pagan A, et al.
Front Dement . 2024 Jul; 2:1198006. PMID: 39081972
Background: Modulation of physical activity represents an important intervention that may delay, slow, or prevent mild cognitive impairment (MCI) or dementia due to Alzheimer's disease (AD). One mechanism proposed to...
4.
Pan A, Audrain M, Sakakibara E, Joshi R, Zhu X, Wang Q, et al.
Front Aging Neurosci . 2024 Jul; 16:1400447. PMID: 39006222
Introduction: Dual specificity protein phosphatase 6 (DUSP6) was recently identified as a key hub gene in a causal gene network that regulates late-onset Alzheimer's disease (AD). Importantly, decreased DUSP6 levels...
5.
Creus-Muncunill J, Haure-Mirande J, Mattei D, Bons J, Ramirez A, Hamilton B, et al.
J Neuroinflammation . 2024 Mar; 21(1):66. PMID: 38459557
Introduction: Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the Huntingtin gene (HTT). Immune activation is abundant in the striatum...
6.
Wang E, Pan A, Bagchi P, Rangaraju S, Seyfried N, Ehrlich M, et al.
Biomolecules . 2024 Jan; 14(1). PMID: 38254666
DUSP4 is a member of the DUSP (dual-specificity phosphatase) subfamily that is selective to the mitogen-activated protein kinases (MAPK) and has been implicated in a range of biological processes and...
7.
Choi J, Ehrlich M, Roussos P, Wang P, Yuan G, Song X
bioRxiv . 2023 Dec; PMID: 38106025
Spatially resolved transcriptomics (SRT) have enabled profiling spatial organization of cells and their transcriptome in situ. Various analytical methods have been developed to uncover cell-cell interaction processes using SRT data....
8.
Tshilenge K, Bons J, Aguirre C, Geronimo-Olvera C, Shah S, Rose J, et al.
Neurobiol Dis . 2023 Dec; 190:106367. PMID: 38042508
X-linked dystonia-parkinsonism (XDP) is a rare neurodegenerative disease endemic to the Philippines. The genetic cause for XDP is an insertion of a SINE-VNTR-Alu (SVA)-type retrotransposon within intron 32 of TATA-binding...
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Wang E, Pan A, Bagchi P, Ranjaraju S, Seyfried N, Ehrlich M, et al.
Res Sq . 2023 Oct; PMID: 37886598
DUSP4 is a member of the DUSP (Dual-Specificity Phosphatase) subfamily that is selective to the mitogen-activated protein kinases (MAPK) and has been implicated in a range of biological processes and...