Scott A Waldman
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Explore the profile of Scott A Waldman including associated specialties, affiliations and a list of published articles.
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192
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2929
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Recent Articles
1.
Baybutt T, Entezari A, Caspi A, Staudt R, Carlson R, Waldman S, et al.
Cancer Biol Ther
. 2024 Sep;
25(1):2398801.
PMID: 39315411
Despite success in treating some hematological malignancies, CAR-T cells have not yet produced similar outcomes in solid tumors due, in part, to the tumor microenvironment, poor persistence, and a paucity...
2.
Cheslow L, Snook A, Waldman S
Biomolecules
. 2024 Apr;
14(4).
PMID: 38672416
Neurological disorders are the leading cause of cognitive and physical disability worldwide, affecting 15% of the global population. Due to the demographics of aging, the prevalence of neurological disorders, including...
3.
Cheslow L, Byrne M, Kopenhaver J, Iacovitti L, Smeyne R, Snook A, et al.
NPJ Parkinsons Dis
. 2024 Apr;
10(1):83.
PMID: 38615030
Mitochondrial dysfunction and reactive oxygen species (ROS) accumulation within the substantia nigra pars compacta (SNpc) are central drivers of dopaminergic (DA) neuron death in Parkinson's disease (PD). Guanylyl cyclases and...
4.
Alexander S, Fabbro D, Kelly E, Mathie A, Peters J, Veale E, et al.
Br J Pharmacol
. 2023 Dec;
180 Suppl 2:S241-S288.
PMID: 38123155
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
5.
Londregan A, Alexander T, Covarrubias M, Waldman S
J Neurochem
. 2023 Dec;
167(6):719-732.
PMID: 38037432
While visceral pain is commonly associated with disorders of the gut-brain axis, underlying mechanisms are not fully understood. Dorsal root ganglion (DRG) neurons innervate visceral structures and undergo hypersensitization in...
6.
Barton J, Londregan A, Alexander T, Entezari A, Covarrubias M, Waldman S
Front Neurosci
. 2023 Nov;
17:1272955.
PMID: 38027512
Enteroendocrine cells (EECs) are an essential interface between the gut and brain that communicate signals about nutrients, pain, and even information from our microbiome. EECs are hormone-producing cells expressed throughout...
7.
Cheslow L, Byrne M, Kopenhaver J, Iacovitti L, Smeyne R, Snook A, et al.
Res Sq
. 2023 Oct;
PMID: 37886524
Mitochondrial dysfunction and reactive oxygen species (ROS) accumulation within the substantia nigra pars compacta (SNpc) are central drivers of dopaminergic (DA) neuron death in Parkinson's disease (PD). Guanylyl cyclases, and...
8.
Barton J, Londregan A, Alexander T, Entezari A, Bar-Ad S, Cheng L, et al.
J Clin Invest
. 2022 Dec;
133(4).
PMID: 36548082
Visceral pain (VP) is a global problem with complex etiologies and limited therapeutic options. Guanylyl cyclase C (GUCY2C), an intestinal receptor producing cyclic GMP(cGMP), which regulates luminal fluid secretion, has...
9.
Crutcher M, Snook A, Waldman S
Expert Rev Clin Pharmacol
. 2022 Oct;
15(11):1317-1326.
PMID: 36259230
Introduction: Colorectal cancer (CRC) is the second most common cause of cancer-related death worldwide. Although overall survival for CRC patients has improved with earlier screening, survival continues to vary substantially...
10.
Caspi A, Entezari A, Crutcher M, Snook A, Waldman S
Per Med
. 2022 Aug;
19(5):457-472.
PMID: 35920071
Colorectal cancer remains a major cause of mortality in the USA, despite advances in prevention and screening. Existing therapies focus primarily on generic treatment such as surgical intervention and chemotherapy,...