Jose I Quetglas
Overview
Explore the profile of Jose I Quetglas including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
740
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0
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Recent Articles
1.
Etxeberria I, Bolanos E, Quetglas J, Gros A, Villanueva A, Palomero J, et al.
Cancer Cell
. 2019 Nov;
36(6):613-629.e7.
PMID: 31761658
Retroviral gene transfer of interleukin-12 (IL-12) into T cells markedly enhances antitumor efficacy upon adoptive transfer but has clinically shown unacceptable severe side effects. To overcome the toxicity, we engineered...
2.
Sanchez-Paulete A, Teijeira A, Quetglas J, Rodriguez-Ruiz M, Sanchez-Arraez A, Labiano S, et al.
Cancer Res
. 2018 Oct;
78(23):6643-6654.
PMID: 30297531
: Multiple lines of evidence indicate a critical role of antigen cross-presentation by conventional BATF3-dependent type 1 classical dendritic cells (cDC1) in CD8-mediated antitumor immunity. Flt3L and XCL1, respectively, constitute...
3.
Ruiz-Guillen M, Gabev E, Quetglas J, Casales E, Ballesteros-Briones M, Poutou J, et al.
Cell Mol Life Sci
. 2016 Apr;
73(20):3897-916.
PMID: 27117550
Alphavirus budding is driven by interactions between nucleocapsids assembled in the cytoplasm and envelope proteins present at the plasma membrane. So far, the expression of capsid and envelope proteins in...
4.
Porrero C, Rodriguez-Moreno J, Quetglas J, Smerdou C, Furuta T, Clasca F
Front Neuroanat
. 2016 Apr;
10:27.
PMID: 27047347
We report a highly efficient, simple, and non-infective method for labeling individual long-range projection neurons (LRPNs) in a specific location with enough sparseness and intensity to allow complete and unambiguous...
5.
Labiano S, Palazon A, Bolanos E, Azpilikueta A, Sanchez-Paulete A, Morales-Kastresana A, et al.
Oncoimmunology
. 2016 Mar;
5(1):e1062967.
PMID: 26942078
Hypoxia is a common feature in solid tumors that has been implicated in immune evasion. Previous studies from our group have shown that hypoxia upregulates the co-stimulatory receptor CD137 on...
6.
Nistal-Villan E, Bunuales M, Poutou J, Gonzalez-Aparicio M, Bravo-Perez C, Quetglas J, et al.
Mol Cancer
. 2015 Dec;
14:210.
PMID: 26671477
Background: The limited efficacy of current treatments against pancreatic cancer has prompted the search of new alternatives such as virotherapy. Activation of the immune response against cancer cells is emerging...
7.
Sanchez-Paulete A, Cueto F, Martinez-Lopez M, Labiano S, Morales-Kastresana A, Rodriguez-Ruiz M, et al.
Cancer Discov
. 2015 Oct;
6(1):71-9.
PMID: 26493961
Unlabelled: Weak and ineffective antitumor cytotoxic T lymphocyte (CTL) responses can be rescued by immunomodulatory mAbs targeting PD-1 or CD137. Using Batf3(-/-) mice, which are defective for cross-presentation of cell-associated...
8.
Weigelin B, Bolanos E, Teijeira A, Martinez-Forero I, Labiano S, Azpilikueta A, et al.
Proc Natl Acad Sci U S A
. 2015 Jun;
112(24):7551-6.
PMID: 26034288
Cancer immunotherapy is undergoing significant progress due to recent clinical successes by refined adoptive T-cell transfer and immunostimulatory monoclonal Ab (mAbs). B16F10-derived OVA-expressing mouse melanomas resist curative immunotherapy with either...
9.
Quetglas J, Labiano S, Aznar M, Bolanos E, Azpilikueta A, Rodriguez I, et al.
Cancer Immunol Res
. 2015 Feb;
3(5):449-54.
PMID: 25691326
Virotherapy and checkpoint inhibitors can be combined for the treatment of cancer with complementarity and potential for synergistic effects. We have developed a cytolytic but nonreplicative viral vector system based...
10.
Melero I, Quetglas J, Reboredo M, Dubrot J, Rodriguez-Madoz J, Mancheno U, et al.
Cancer Res
. 2014 Dec;
75(3):497-507.
PMID: 25527611
Host responses are increasingly considered important for the efficacious response to experimental cancer therapies that employ viral vectors, but little is known about the specific nature of host responses required....