Jorge L O Domingos
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Explore the profile of Jorge L O Domingos including associated specialties, affiliations and a list of published articles.
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5
Citations
7
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Recent Articles
1.
de Souza L, Salustiano E, da Costa K, Costa A, Rumjanek V, Domingos J, et al.
Bioorg Chem
. 2021 Mar;
110:104790.
PMID: 33743223
α-aryl-α-tetralones and α-fluoro-α-aryl-α-tetralones derivatives were synthesized by palladium catalyzed α-arylation reaction of α-tetralones and α-fluoro-α-tetralones, with bromoarenes in moderate to good yields. These compounds were evaluated for their in vitro...
2.
Caleffi G, Brum J, Costa A, Domingos J, Costa P
J Org Chem
. 2021 Mar;
86(6):4849-4858.
PMID: 33683900
3-Arylidenechroman-4-ones and 2-arylidene-1-tetralones are hydrogenated to -benzylic alcohols in dr's and er's up to 99:1 via a C═C and C═O one-pot reduction in the presence of 2-5 mol % Noyori-Ikariya-type...
3.
Gaspar F, Marques Ribeiro S, Barcellos J, Monteiro S, Domingos J, Luciano M, et al.
Bioorg Chem
. 2021 Jan;
107:104584.
PMID: 33453646
Natural pterocarpans and synthetic 5-carba-pterocarpans are isosteres in which the oxygen atom at position 5 in the pyran-ring of pterocarpans is replaced by a methylene group. These 5-carba-analogues were obtained...
4.
Fernandes T, Manvar D, Domingos J, Basu A, Nichols D, Kaushik-Basu N, et al.
Eur J Med Chem
. 2016 Feb;
112:33-38.
PMID: 26874742
The synthesis of a series of 5-carba-pterocarpens derivatives involving the cyclization of α-aryl-α-tetralones is described. Several compounds demonstrated potent activity and selectivity in vitro against HCV replicon reporter cells. The...
5.
Manvar D, Fernandes T, Domingos J, Baljinnyam E, Basu A, Junior E, et al.
Eur J Med Chem
. 2015 Feb;
93:51-4.
PMID: 25644675
The synthesis of a novel series of 1-carba-isoflavanones through the α-arylation of α-tetralones is described. Several of these compounds demonstrated potent activity and selectivity in-vitro against HCV replicon reporter cells....