Jordan L Meier
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Explore the profile of Jordan L Meier including associated specialties, affiliations and a list of published articles.
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97
Citations
2197
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Recent Articles
1.
Inhibition of Ribosome Biogenesis in vivo Causes p53-Dependent Death and p53-Independent Dysfunction
Cho C, Nguyen T, Rougeau A, Huang Y, To S, Lin X, et al.
Cell Mol Gastroenterol Hepatol
. 2025 Mar;
:101496.
PMID: 40081569
Background & Aims: While it is well-known that ribosomes are critical for cell function, and their synthesis (known as ribosome biogenesis; "RiBi") is energy-intensive, surprisingly little is known about RiBi...
2.
Sengupta R, Brodsky O, Bingham P, Diehl W, Ferre R, Greasley S, et al.
J Biol Chem
. 2025 Feb;
301(3):108262.
PMID: 39909374
The MYST family of lysine acetyltransferases are transcriptional regulators often dysregulated in cancer. In cells, MYST members form distinct multiprotein complexes that guide their histone substrate specificity, but how this...
3.
Penikalapati M, Meier J
Nat Rev Mol Cell Biol
. 2024 Oct;
26(2):83.
PMID: 39455863
No abstract available.
4.
Najera S, Ricketts C, Schmidt L, Medina J, Saito K, Ileva L, et al.
Mol Cancer Ther
. 2024 Oct;
24(2):200-213.
PMID: 39397296
Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an inherited cancer syndrome caused by germline pathogenic variants in the fumarate hydratase (FH) gene. Affected individuals are at risk for developing...
5.
Cho C, Nguyen T, Rougeau A, Huang Y, To S, Lin X, et al.
bioRxiv
. 2024 Oct;
PMID: 39386693
Ribosomes are critical for cell function; their synthesis (known as ribosome biogenesis; "RiBi") is complex and energy-intensive. Surprisingly little is known about RiBi in differentiated cells in adult tissue. Here,...
6.
Chen X, Crawford M, Xiong Y, Shaik A, Suazo K, Bauer L, et al.
JACS Au
. 2024 Aug;
4(8):3094-3103.
PMID: 39211607
The transcriptional coactivators EP300 and CREBBP are critical regulators of gene expression that share high sequence identity but exhibit nonredundant functions in basal and pathological contexts. Here, we report the...
7.
Thalalla Gamage S, Khoogar R, Manage S, Crawford M, Georgeson J, Polevoda B, et al.
bioRxiv
. 2024 Aug;
PMID: 39091849
Transfer RNA (tRNA) modifications are crucial for protein synthesis, but their position-specific physiological roles remain poorly understood. Here we investigate the impact of N4-acetylcytidine (acC), a highly conserved tRNA modification,...
8.
Chen X, Crawford M, Xiong Y, Shaik A, Suazo K, Penkalapati M, et al.
bioRxiv
. 2024 May;
PMID: 38746397
The transcriptional coactivators EP300 and CREBBP are critical regulators of gene expression that share high sequence identity but exhibit non-redundant functions in basal and pathological contexts. Here, we report the...
9.
Zhou M, Thalalla Gamage S, Tran K, Bartee D, Wei X, Yin B, et al.
bioRxiv
. 2024 Apr;
PMID: 38585770
Human NAT10 acetylates the N4 position of cytidine in RNA, predominantly on rRNA and tRNA, to facilitate ribosome biogenesis and protein translation. NAT10 has been proposed as a therapeutic target...
10.
Amin R, Ha N, Qiu T, Holewinski R, Lam K, Lopes A, et al.
bioRxiv
. 2024 Feb;
PMID: 38410432
Acetylation of protein and RNA represent a critical event for development and cancer progression. NAT10 is the only known RNA acetylase that catalyzes the N4-actylcytidine (ac4C) modification of RNAs. Here,...