Joost P M van Meerwijk
Overview
Explore the profile of Joost P M van Meerwijk including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Thiault N, Darrigues J, Adoue V, Gros M, Binet B, Perals C, et al.
Nat Immunol
. 2015 May;
16(6):628-34.
PMID: 25939024
Most T lymphocytes, including regulatory T cells (Treg cells), differentiate in the thymus. The age-dependent involution of this organ leads to decreasing production of T cells. Here we found that...
12.
Pasquet L, Douet J, Sparwasser T, Romagnoli P, van Meerwijk J
Blood
. 2013 Apr;
121(21):4303-10.
PMID: 23580663
Despite the use of immunosuppressive drugs, chronic allograft rejection remains a major hurdle in transplantation medicine. Induction of specific immunologic tolerance to antigens expressed by the graft would avoid its...
13.
Tellier J, Andrianjaka A, Vicente R, Thiault N, Enault G, Garchon H, et al.
Eur J Immunol
. 2013 Feb;
43(5):1356-62.
PMID: 23400928
Regulatory T (Treg) lymphocytes play a central role in the control of autoimmune pathology. Any alteration in Treg-cell biology in mouse strains used for the study of these disorders therefore...
14.
Romagnoli P, Dooley J, Enault G, Vicente R, Malissen B, Liston A, et al.
J Immunol
. 2012 Sep;
189(8):3831-7.
PMID: 22988035
Thymus-derived CD4(+)Foxp3(+) regulatory T lymphocytes (Tregs) play a central role in the suppression of immune responses to self-antigens and thus avoid autoimmune disorders. It remains unclear if the specialized thymic...
15.
Pasquet L, Joffre O, Santolaria T, van Meerwijk J
Front Immunol
. 2012 May;
2:80.
PMID: 22566869
The immunosuppressive regimens currently used in transplantation to prevent allograft destruction by the host's immune system have deleterious side effects and fail to control chronic rejection processes. Induction of donor-specific...
16.
Pomie C, Vicente R, Vuddamalay Y, Ardesjo Lundgren B, Van der Hoek M, Enault G, et al.
Proc Natl Acad Sci U S A
. 2011 Jul;
108(30):12437-42.
PMID: 21746930
Mutations in the gene encoding the transcription factor autoimmune regulator (AIRE) are responsible for autoimmune polyendocrinopathy candidiasis ectodermal dystrophy syndrome. AIRE directs expression of tissue-restricted antigens in the thymic medulla...
17.
Nouze C, Pasquet L, van Meerwijk J
Methods Mol Biol
. 2011 Feb;
707:187-96.
PMID: 21287336
Regulatory T lymphocytes expressing CD4, high levels of CD25, and the transcription factor Foxp3 play a crucial role in the control of immune responses to self and nonself antigens. In...
18.
Romagnoli P, van Meerwijk J
Prog Mol Biol Transl Sci
. 2010 Aug;
92:251-77.
PMID: 20800824
Regulatory T lymphocytes play a central role in the control of a variety of immune-responses. Their absence in humans and in experimental animal models leads to severe autoimmune and inflammatory...
19.
Pomie C, Menager-Marcq I, van Meerwijk J
Hum Immunol
. 2008 Sep;
69(11):708-14.
PMID: 18817827
Regulatory T lymphocytes unequivocally play a major role in the maintenance of immunologic homeostasis. The first descriptions of regulatory T lymphocytes concerned CD8(+) cells, but this field was brought into...
20.
Joffre O, Santolaria T, van Meerwijk J
Med Sci (Paris)
. 2008 Sep;
24(8-9):689-91.
PMID: 18789210
No abstract available.