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Progress in Molecular Biology and Translational Science

'Progress in Molecular Biology and Translational Science' is a prestigious journal that focuses on cutting-edge research in the field of molecular biology and its applications in translational science. It covers a wide range of topics including genomics, proteomics, bioinformatics, and drug discovery, providing valuable insights into the latest advancements and their potential impact on human health and disease.

Details
Abbr. Prog Mol Biol Transl Sci
Start 2008
End Continuing
p-ISSN 1877-1173
e-ISSN 1878-0814
Country Netherlands
Language English
Specialty Molecular Biology
Metrics
h-index / Ranks: 2493 113
SJR / Ranks: 14815 133
CiteScore / Ranks: 2975 6.90
Recent Articles
1.
Dar T, Singh L, Uversky V
Prog Mol Biol Transl Sci . 2025 Feb; 211:xiii-xiv. PMID: 39947756
No abstract available.
2.
Singh K, Krishna S, Gupta A, Singh L
Prog Mol Biol Transl Sci . 2025 Feb; 211:89-111. PMID: 39947755
Proteins are responsible for a vast majority of various cellular effector processes. α-crystallin is one of the most important proteins in the lens of the eye, which acts as a...
3.
Ahanger I, Hajam I, Wani O
Prog Mol Biol Transl Sci . 2025 Feb; 211:63-87. PMID: 39947754
Understanding the factors capable of modulation of conformational stability and aggregation propensity of α-synuclein (α-Syn), a hallmark of Parkinson's disease (PD), is crucial for developing future therapeutic interventions for this...
4.
Nicholson V, Meese E, Boothby T
Prog Mol Biol Transl Sci . 2025 Feb; 211:39-61. PMID: 39947753
Desiccation, the extreme loss of water, poses a significant challenge to living organisms. Desiccation-tolerant organisms combat this in part by accumulating desiccation tolerance intrinsically disordered proteins (DT-IDPs) and osmolytes within...
5.
Singh K, Verma R, Singh N, Singh L, Gupta A
Prog Mol Biol Transl Sci . 2025 Feb; 211:271-292. PMID: 39947752
Aggregation of α-Synuclein (α-Syn) is the hallmark of the pathophysiology of Parkinson's disease. Apart from aggregates, α-Syn can exist in multiple abnormal forms such as oligomers, protofibrils, fibrils amorphous aggregates...
6.
Priyanka G, Raj E, Prabhu N
Prog Mol Biol Transl Sci . 2025 Feb; 211:249-269. PMID: 39947751
The formation of membraneless organelles is vital for the intracellular organization of macromolecules and in regulating many cellular processes. The membraneless organelles are formed by liquid-liquid phase separation (LLPS) mainly...
7.
Chatterjee H, Sengupta N
Prog Mol Biol Transl Sci . 2025 Feb; 211:209-247. PMID: 39947750
In recent decades, the conventional protein folding paradigm has been challenged by intriguing properties of disordered peptide sequences that do not adopt stably folded conformations. Such intrinsically disordered proteins and...
8.
Bhat M
Prog Mol Biol Transl Sci . 2025 Feb; 211:17-38. PMID: 39947749
Intrinsically disordered proteins (IDPs), despite lacking a stable structure, play crucial role in majority of the cellular processes. Casein, a key milk protein, represents this category of proteins, due to...
9.
Khan S, Bano N, Uversky V, Ahamad S, Bhat S
Prog Mol Biol Transl Sci . 2025 Feb; 211:169-207. PMID: 39947748
Huntington's disease (HD) is a progressive neurodegenerative condition resulting from a CAG repeat expansion in the huntingtin gene (HTT). Recent advancements in understanding HD's cellular and molecular pathways have paved...
10.
Hassan M, Hussain M, Khan R
Prog Mol Biol Transl Sci . 2025 Feb; 211:145-168. PMID: 39947747
One of the hallmarks of multiple neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, is deposition of insoluble amyloid fibrils, which are toxic proteinaceous structures containing cross β-sheets. Several inhibitory...