Jonathan R Chubb
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Explore the profile of Jonathan R Chubb including associated specialties, affiliations and a list of published articles.
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47
Citations
1945
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Recent Articles
1.
Antolovic V, Chubb J
Methods Mol Biol
. 2024 Jul;
2814:223-245.
PMID: 38954209
Dictyostelium represents a stripped-down model for understanding how cells make decisions during development. The complete life cycle takes around a day and the fully differentiated structure is composed of only...
2.
Jenkins D, Chubb J, Galea G
Philos Trans R Soc Lond B Biol Sci
. 2024 Mar;
379(1900):20230043.
PMID: 38432319
No abstract available.
3.
Priessner M, Gaboriau D, Sheridan A, Lenn T, Garzon-Coral C, Dunn A, et al.
Nat Methods
. 2024 Jan;
21(2):322-330.
PMID: 38238557
The development of high-resolution microscopes has made it possible to investigate cellular processes in 3D and over time. However, observing fast cellular dynamics remains challenging because of photobleaching and phototoxicity....
4.
Westbrook E, Lenn T, Chubb J, Antolovic V
Development
. 2023 Nov;
150(23).
PMID: 37921687
Development can proceed in 'fits and starts', with rapid transitions between cell states involving concerted transcriptome-wide changes in gene expression. However, it is not clear how these transitions are regulated...
5.
Westbrook E, Ford H, Antolovic V, Chubb J
Development
. 2023 Oct;
150(19).
PMID: 37831057
The distribution of mRNA in tissue is determined by the balance between transcription and decay. Understanding the control of RNA decay during development has been somewhat neglected compared with transcriptional...
6.
Ford H, Manhart A, Chubb J
Elife
. 2023 Mar;
12.
PMID: 36856269
Cells use signal relay to transmit information across tissue scales. However, the production of information carried by signal relay remains poorly characterised. To determine how the coding features of signal...
7.
Williams R, Chubb J, Insall R, King J, Pears C, Thompson E, et al.
Cells
. 2021 Nov;
10(11).
PMID: 34831258
The social amoeba provides an excellent model for research across a broad range of disciplines within biology. The organism diverged from the plant, yeast, fungi and animal kingdoms around 1...
8.
Chubb J, Ford H, Antolovic V
Dev Cell
. 2021 Aug;
56(15):2142-2144.
PMID: 34375580
A persistent view of cell fate choices during development entails centralized control by so-called master regulators. A recent single-cell study of the large-scale fate specification during mammalian gastrulation (Mittnenzweig et ...
9.
Nichols J, Antolovic V, Reich J, Brameyer S, Paschke P, Chubb J
Elife
. 2020 Apr;
9.
PMID: 32255425
Dedifferentiation is a critical response to tissue damage, yet is not well understood, even at a basic phenomenological level. Developing cells undergo highly efficient dedifferentiation, completed by most cells within...
10.
Tunnacliffe E, Chubb J
Trends Genet
. 2020 Feb;
36(4):288-297.
PMID: 32035656
The idea that gene activity can be discontinuous will not surprise many biologists - many genes are restricted in when and where they can be expressed. Yet during the past...