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Danielle Cannon

Explore the profile of Danielle Cannon including associated specialties, affiliations and a list of published articles. Areas
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Citations 222
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Recent Articles
1.
Fessler J, Ting S, Yi H, Haase S, Chen J, Gulec S, et al.
NAR Cancer . 2024 Aug; 6(3):zcae035. PMID: 39091515
Recently, the cancer community has gained a heightened awareness of the roles of extrachromosomal DNA (ecDNA) in cancer proliferation, drug resistance and epigenetic remodeling. However, a hindrance to studying ecDNA...
2.
Cannon D, Eichhorn S, Donald A
ACS Omega . 2019 Aug; 1(5):915-922. PMID: 31457172
Under denaturing conditions such as low pH and elevated temperatures, proteins in vitro can misfold and aggregate to form long rigid rods called amyloid fibrils; further self-assembly can lead to...
3.
Cannon D, Buys N, Sriram K, Sharma S, Morris N, Sun J
Respir Med . 2016 Nov; 121:81-90. PMID: 27888996
This article aimed to analyse the outcome of self-management randomised control trials and their impact upon chronic obstructive pulmonary disease patients' health outcomes using meta-analysis approach. PubMed, Scopus, CINAHL, Web...
4.
Corrigan A, Tunnacliffe E, Cannon D, Chubb J
Elife . 2016 Feb; 5. PMID: 26896676
Transcription occurs in stochastic bursts. Early models based upon RNA hybridisation studies suggest bursting dynamics arise from alternating inactive and permissive states. Here we investigate bursting mechanism in live cells...
5.
Cannon D, Corrigan A, Miermont A, McDonel P, Chubb J
Development . 2015 Jul; 142(16):2840-9. PMID: 26209649
Much of development and disease concerns the generation of gene expression differences between related cells sharing similar niches. However, most analyses of gene expression only assess population and time-averaged levels...
6.
Chubb J, Stevense M, Cannon D, Muramoto T, Corrigan A
Methods Mol Biol . 2013 Aug; 1042:101-13. PMID: 23980003
Dictyostelium cells have great utility for live imaging of single gene transcriptional dynamics. The cells allow efficient molecular genetics, for targeting of RNA reporters and fluorescent proteins to individual, defined...
7.
Muramoto T, Cannon D, Gierlinski M, Corrigan A, Barton G, Chubb J
Proc Natl Acad Sci U S A . 2012 Apr; 109(19):7350-5. PMID: 22529358
Transcription of genes can be discontinuous, occurring in pulses or bursts. It is not clear how properties of transcriptional pulses vary between different genes. We compared the pulsing of five...
8.
Cannon D, Chubb J
EMBO Rep . 2011 Nov; 12(12):1208-10. PMID: 22094274
No abstract available.
9.
Exley C, House E, Collingwood J, Davidson M, Cannon D, Donald A
J Alzheimers Dis . 2010 Apr; 20(4):1159-65. PMID: 20413877
Several amyloidogenic proteins including insulin, beta-lactoglobulin, and albumin form spherulites in vitro under non-physiological conditions. These micrometer-sized, roughly spherical structures are composed of ordered arrays of amyloid fibrils in radial...
10.
Krebs M, Domike K, Cannon D, Donald A
Faraday Discuss . 2008 Dec; 139:265-74. PMID: 19049000
The importance of misfolding proteins forming amyloid fibrils for the aetiology of many diseases, particularly those of old age, is well recognized. This phenomenon is now thought to be a...