Jonathan N Wells
Overview
Explore the profile of Jonathan N Wells including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
735
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chang N, Wells J, Wang A, Schofield P, Huang Y, Truong V, et al.
bioRxiv
. 2024 Apr;
PMID: 38585793
Transposable elements (TEs) make up the bulk of eukaryotic genomes and examples abound of TE-derived sequences repurposed for organismal function. The process by which TEs become coopted remains obscure because...
2.
Wells J, Chang N, McCormick J, Coleman C, Ramos N, Jin B, et al.
Genome Res
. 2023 Sep;
33(8):1325-1339.
PMID: 37714714
Cys2-His2 zinc finger genes (ZNFs) form the largest family of transcription factors in metazoans. ZNF evolution is highly dynamic and characterized by the rapid expansion and contraction of numerous subfamilies...
3.
Quidwai T, Wang J, Hall E, Petriman N, Leng W, Kiesel P, et al.
Elife
. 2021 Nov;
10.
PMID: 34734804
Intraflagellar transport (IFT) is a highly conserved mechanism for motor-driven transport of cargo within cilia, but how this cargo is selectively transported to cilia is unclear. WDR35/IFT121 is a component...
4.
Wells J, Feschotte C
Annu Rev Genet
. 2020 Sep;
54:539-561.
PMID: 32955944
Transposable elements (TEs) are mobile DNA sequences that propagate within genomes. Through diverse invasion strategies, TEs have come to occupy a substantial fraction of nearly all eukaryotic genomes, and they...
5.
Bergendahl L, Gerasimavicius L, Miles J, Macdonald L, Wells J, Welburn J, et al.
Protein Sci
. 2019 Jun;
28(8):1400-1411.
PMID: 31219644
Many human genetic disorders are caused by mutations in protein-coding regions of DNA. Taking protein structure into account has therefore provided key insight into the molecular mechanisms underlying human genetic...
6.
Brennan C, Vaites L, Wells J, Santaguida S, Paulo J, Storchova Z, et al.
Genes Dev
. 2019 Jun;
33(15-16):1031-1047.
PMID: 31196865
Aneuploidy, a condition characterized by chromosome gains and losses, causes reduced fitness and numerous cellular stresses, including increased protein aggregation. Here, we identify protein complex stoichiometry imbalances as a major...
7.
Wells J, Marsh J
Methods Mol Biol
. 2018 Oct;
1851:251-261.
PMID: 30298401
Reconstructing evolutionary relationships in repeat proteins is notoriously difficult due to the high degree of sequence divergence that typically occurs between duplicated repeats. This is complicated further by the fact...
8.
Pan J, Meyers R, Michel B, Mashtalir N, Sizemore A, Wells J, et al.
Cell Syst
. 2018 May;
6(5):555-568.e7.
PMID: 29778836
Protein complexes are assemblies of subunits that have co-evolved to execute one or many coordinated functions in the cellular environment. Functional annotation of mammalian protein complexes is critical to understanding...
9.
Wells J, Bergendahl L, Marsh J
Methods Mol Biol
. 2018 Apr;
1764:347-356.
PMID: 29605926
Sequence and structure space are nowadays sufficiently large that we can use computational methods to model the structure of proteins based on sequence similarity alone. Not only useful as a...
10.
Wells J, Marsh J
Methods Mol Biol
. 2018 Apr;
1764:3-27.
PMID: 29605905
Experimental methods for the characterization of protein complexes have been instrumental in achieving our current understanding of the protein universe and continue to progress with each year that passes. In...