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Jonathan N Wells

Explore the profile of Jonathan N Wells including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 735
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11.
Wells J, Gligoris T, Nasmyth K, Marsh J
Curr Biol . 2017 Jan; 27(1):R17-R18. PMID: 28073014
Mitotic chromosome condensation, sister chromatid cohesion, and higher order folding of interphase chromatin are mediated by condensin and cohesin, eukaryotic members of the SMC (structural maintenance of chromosomes)-kleisin protein family....
12.
Natan E, Wells J, Teichmann S, Marsh J
Curr Opin Struct Biol . 2016 Dec; 42:90-97. PMID: 27969102
Most proteins assemble into complexes, which are involved in almost all cellular processes. Thus it is crucial for cell viability that mechanisms for correct assembly exist. The timing of assembly...
13.
McShane E, Sin C, Zauber H, Wells J, Donnelly N, Wang X, et al.
Cell . 2016 Oct; 167(3):803-815.e21. PMID: 27720452
Do young and old protein molecules have the same probability to be degraded? We addressed this question using metabolic pulse-chase labeling and quantitative mass spectrometry to obtain degradation profiles for...
14.
Wells J, Bergendahl L, Marsh J
Cell Rep . 2016 Jan; 14(4):679-685. PMID: 26804901
The assembly of heteromeric protein complexes is an inherently stochastic process in which multiple genes are expressed separately into proteins, which must then somehow find each other within the cell....
15.
Wells J, Bergendahl L, Marsh J
Biochem Soc Trans . 2015 Nov; 43(6):1221-6. PMID: 26614664
The interaction of biological macromolecules is a fundamental attribute of cellular life. Proteins, in particular, often form stable complexes with one another. Although the importance of protein complexes is widely...