Jon C Cook
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Explore the profile of Jon C Cook including associated specialties, affiliations and a list of published articles.
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21
Citations
317
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Recent Articles
11.
Criswell K, Cook J, Morse D, Lawton M, Somps C, Obert L, et al.
Toxicol Sci
. 2012 Apr;
128(1):42-56.
PMID: 22539613
The preceding article identified key components of pregabalin's mode of action on nongenotoxic hemangiosarcoma formation in mice, including increased serum bicarbonate leading to decreased respiratory rate, increased blood pH, increased...
12.
Laifenfeld D, Gilchrist A, Drubin D, Jorge M, Eddy S, Frushour B, et al.
Toxicol Sci
. 2009 Oct;
113(1):254-66.
PMID: 19812364
To understand the molecular mechanisms underlying compound-induced hemangiosarcomas in mice, and therefore, their human relevance, a systems biology approach was undertaken using transcriptomics and Causal Network Modeling from mice treated...
13.
Cohen S, Storer R, Criswell K, Doerrer N, Dellarco V, Pegg D, et al.
Toxicol Sci
. 2009 Jun;
111(1):4-18.
PMID: 19525443
Although rarely occurring in humans, hemangiosarcomas (HS) have become important in evaluating the potential human risk of several chemicals, including industrial, agricultural, and pharmaceutical agents. Spontaneous HS arise frequently in...
14.
Klaunig J, Babich M, Cook J, David R, DeLuca J, McKee R, et al.
Environ Health Perspect
. 2007 Mar;
115(1):A14-5.
PMID: 17366801
No abstract available.
15.
Cappon G, Fleeman T, Rocca M, Cook J, Hurtt M
Birth Defects Res B Dev Reprod Toxicol
. 2004 Jan;
68(5):421-7.
PMID: 14745992
Background: Hoshi et al. [Hoshi et al. J Toxicol Sci 10(Suppl):187-255, 1985a,b,c,d] evaluated the potential for hydroxypropyl methylcellulose acetate succinate (HPMCAS) to produce developmental and reproductive toxicity in a series...
16.
Klaunig J, Babich M, Baetcke K, Cook J, Corton J, David R, et al.
Crit Rev Toxicol
. 2004 Jan;
33(6):655-780.
PMID: 14727734
Widely varied chemicals--including certain herbicides, plasticizers, drugs, and natural products--induce peroxisome proliferation in rodent liver and other tissues. This phenomenon is characterized by increases in the volume density and fatty...
17.
Gupta U, Cook J, Tassinari M, Hurtt M
Birth Defects Res B Dev Reprod Toxicol
. 2003 Jul;
68(1):27-37.
PMID: 12852481
Background: Analysis of the literature for nonsteroidal anti-inflammatory drugs (NSAIDs) suggests that a low incidence of developmental anomalies occurs in rats given NSAIDs on specific days during organogenesis. Aspirin (acetylsalicylic...
18.
Cook J, Jacobson C, Gao F, Tassinari M, Hurtt M, DeSesso J
Birth Defects Res B Dev Reprod Toxicol
. 2003 Jul;
68(1):5-26.
PMID: 12852480
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed to pregnant women. Some case-control studies have linked the NSAIDs aspirin and indomethacin with a risk of congenital abnormalities...
19.
Tassinari M, Cook J, Hurtt M
Birth Defects Res B Dev Reprod Toxicol
. 2003 Jul;
68(1):3-4.
PMID: 12852479
No abstract available.
20.
Daston G, Cook J, Kavlock R
Toxicol Sci
. 2003 May;
74(2):245-52.
PMID: 12730617
The hypothesis that hormonally active compounds in the environment--endocrine disrupters--are having a significant impact on human and ecological health has captured the public's attention like no other toxicity concern since...