John E Wiktorowicz
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Explore the profile of John E Wiktorowicz including associated specialties, affiliations and a list of published articles.
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37
Citations
693
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Recent Articles
1.
Jovasevic V, Zhang H, Sananbenesi F, Guedea A, Soman K, Wiktorowicz J, et al.
iScience
. 2021 Jun;
24(6):102617.
PMID: 34142063
It is well established that the formation of episodic memories requires multiple hippocampal mechanisms operating on different time scales. Early mechanisms of memory formation (synaptic consolidation) have been extensively characterized....
2.
Dillon E, Soman K, Wiktorowicz J, Sur R, Jupiter D, Danesi C, et al.
PLoS One
. 2019 Jun;
14(6):e0217690.
PMID: 31194764
Introduction: Long-term head-down bed rest (HDBR) results in musculoskeletal losses similar to those observed during long-term space flight. Agents such as testosterone, in addition to regular exercise, are effective countermeasures...
3.
Wiktorowicz J, Chowdhury I, Stafford S, Choudhuri S, Dey N, Garg N
Mediators Inflamm
. 2019 Jun;
2019:3481430.
PMID: 31182931
Macrophages (M) play a central role in coordinating host response to pathogens, cellular injury, and environmental stimuli. Herein, we report multidimensional, nuclear proteomic analyses of protein expression and posttranslational modifications...
4.
Wiktorowicz J, Zago M, Garg N
Methods Mol Biol
. 2019 Mar;
1955:363-380.
PMID: 30868541
The thiol moieties of cysteinyl residues in proteins undergo a number of modifications including nitrosylation, oxidation, persulfidation, sulfenylation, and others. These protein modifications may influence gain as well as loss...
5.
Zago M, Wiktorowicz J, Spratt H, Koo S, Barrientos N, Nunez Burgos A, et al.
Front Microbiol
. 2019 Jan;
9:3320.
PMID: 30697201
infection causes Chagas disease (ChD) presented by dilated cardiomyopathy and heart failure. During infection, oxidative and nitrosative stresses are elicited by the immune cells for control the pathogen; however, excess...
6.
Zolochevska O, Bjorklund N, Woltjer R, Wiktorowicz J, Taglialatela G
J Alzheimers Dis
. 2018 Aug;
65(2):659-682.
PMID: 30103319
Some individuals, here referred to as Non-Demented with Alzheimer's Neuropathology (NDAN), retain their cognitive function despite the presence of amyloid plaques and tau tangles typical of symptomatic Alzheimer's disease (AD)....
7.
Bhopale K, Amer S, Kaphalia L, Soman K, Wiktorowicz J, Shakeel Ansari G, et al.
Alcohol Clin Exp Res
. 2017 Aug;
41(10):1675-1685.
PMID: 28792616
Background: Chronic alcohol abuse, a major risk factor for such diseases as hepatitis and cirrhosis, impairs hepatic alcohol dehydrogenase (ADH; key ethanol [EtOH]-metabolizing enzyme). Therefore, differentially altered hepatic and plasma...
8.
Soman K, Stafford S, Pazdrak K, Wu Z, Luo X, White W, et al.
J Proteome Res
. 2017 Jul;
16(8):2663-2679.
PMID: 28679203
Activated eosinophils contribute to airway dysfunction and tissue remodeling in asthma and thus are considered to be important factors in asthma pathology. We report here comparative proteomic and phosphoproteomic changes...
9.
Bhopale K, Amer S, Kaphalia L, Soman K, Wiktorowicz J, Shakeel Ansari G, et al.
Pancreas
. 2017 Jun;
46(6):806-812.
PMID: 28609370
Objectives: The aim of this study was to identify differentially expressed proteins in the pancreatic tissue of hepatic alcohol dehydrogenase-deficient deer mice fed ethanol to understand metabolic basis and mechanism...
10.
Wiktorowicz J, Soman K
Adv Exp Med Biol
. 2016 Dec;
919:443-462.
PMID: 27975230
Properly performed, biomarker discovery can lead to effective candidates that can ultimately serve as predictors of disease, medical condition, define therapeutic parameters, and many other applications in medicine. Preferably, biomarkers...