Allan R Brasier
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Explore the profile of Allan R Brasier including associated specialties, affiliations and a list of published articles.
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235
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7468
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Recent Articles
1.
Brasier A
Expert Rev Respir Med
. 2025 Jan;
19(1):29-41.
PMID: 39745473
Introduction: In genetically predisposed individuals, exposure to aeroallergens and infections from RNA viruses shape epithelial barrier function, leading to Allergic Asthma (AA). Here, activated pattern recognition receptors (PRRs) in lower...
2.
Casey S, Burnside E, Brasier A
J Clin Transl Sci
. 2024 Nov;
8(1):e162.
PMID: 39540108
External advisory committees (EACs) are critical peer-review meetings that drive improvement at Clinical and Translational Science Award Program Hubs. Despite their ubiquity, evaluations of EAC optimization and effective implementation remain...
3.
Brasier A, Zhao Y, Chung K
Front Immunol
. 2024 Jul;
15:1435120.
PMID: 39044815
No abstract available.
4.
Skibba M, Brasier A
Am J Physiol Lung Cell Mol Physiol
. 2024 May;
327(1):L86-L101.
PMID: 38713619
The mechanisms how aeroallergens induce sensitization are incompletely understood. The house dust mite (HDM) (Der p) is a ubiquitous aeroallergen that represents a major cause of allergic rhinitis and asthma....
5.
Xu X, Qiao D, Brasier A
Front Immunol
. 2024 Apr;
15:1366235.
PMID: 38601157
Introduction: The human orthopneumovirus, Respiratory Syncytial Virus (RSV), is the causative agent of severe lower respiratory tract infections (LRTI) and exacerbations of chronic lung diseases. In immune competent hosts, RSV...
6.
Sweeney W, Kelly P, Brasier A, Rolland B
J Clin Transl Sci
. 2023 Nov;
7(1):e233.
PMID: 38028334
The Clinical and Translational Science Awards (CTSA) Program supports a national network of medical research institutions working to improve the translational process. High-performing translational teams (TTs) are critical for advancing...
7.
Brasier A, Casey S, Hatfield P, Kelly P, Sweeney W, Schweizer M, et al.
J Clin Transl Sci
. 2023 Sep;
7(1):e171.
PMID: 37745935
Despite understanding its impact on organizational effectiveness, practical guidance on how to train translational team (TT) leaders is lacking. Previously, we developed an evolutionary learning model of TT maturation consisting...
8.
Pan L, Vlahopoulos S, Tanner L, Bergwik J, Bacsi A, Radak Z, et al.
Front Immunol
. 2023 Aug;
14:1186369.
PMID: 37614238
Recent advances have uncovered the non-random distribution of 7, 8-dihydro-8-oxoguanine (8-oxoGua) induced by reactive oxygen species, which is believed to have epigenetic effects. Its cognate repair protein, 8-oxoguanine DNA glycosylase...
9.
Xue Y, Pan L, Vlahopoulos S, Wang K, Zheng X, Radak Z, et al.
Front Immunol
. 2023 Aug;
14:1161160.
PMID: 37600772
Interferons (IFNs) are secreted cytokines with the ability to activate expression of IFN stimulated genes that increase resistance of cells to virus infections. Activated transcription factors in conjunction with chromatin...
10.
Qiao D, Xu X, Zhang Y, Yang J, Brasier A
Front Immunol
. 2023 Aug;
14:1197356.
PMID: 37564646
Introduction: The unfolded protein response (UPR) has emerged as an important signaling pathway mediating anti-viral defenses to Respiratory Syncytial Virus (RSV) infection. Earlier we found that RSV replication predominantly activates...