Joel E Kleinman
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Explore the profile of Joel E Kleinman including associated specialties, affiliations and a list of published articles.
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206
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Recent Articles
1.
Zhou Y, Su Y, Yang Q, Li J, Hong Y, Gao T, et al.
bioRxiv
. 2025 Mar;
PMID: 40027814
Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis contribute to plasticity, learning and memory, but their evolutionary changes across species and specialized features in humans remain poorly understood....
2.
Ramnauth A, Tippani M, Divecha H, Papariello A, Miller R, Nelson E, et al.
Cell Rep
. 2025 Feb;
44(2):115300.
PMID: 40009515
The dentate gyrus of the hippocampus is important for many cognitive functions, including learning, memory, and mood. Here, we present transcriptome-wide spatial gene expression maps of the human dentate gyrus...
3.
Zhou J, Luo C, Liu H, Heffel M, Straub R, Kleinman J, et al.
Cell Genom
. 2025 Feb;
5(3):100774.
PMID: 39986279
DNA methylation (DNAm) is a key epigenetic mark with essential roles in gene regulation, mammalian development, and human diseases. Single-cell technologies enable profiling DNAm at cytosines in individual cells, but...
4.
Phillips 3rd R, Oh S, Bach S, Du Y, Miller R, Kleinman J, et al.
iScience
. 2025 Feb;
28(2):111820.
PMID: 39967863
The lateral septum (LS) is a midline, subcortical structure that is a critical regulator of social behaviors. Mouse studies have identified molecularly distinct neuronal populations within the LS, which control...
5.
Katrinli S, Wani A, Maihofer A, Ratanatharathorn A, Daskalakis N, Montalvo-Ortiz J, et al.
Genome Med
. 2024 Dec;
16(1):147.
PMID: 39696436
Background: The occurrence of post-traumatic stress disorder (PTSD) following a traumatic event is associated with biological differences that can represent the susceptibility to PTSD, the impact of trauma, or the...
6.
Breen M, Tao R, Yang A, Wang X, Amini P, de Los Santos M, et al.
medRxiv
. 2024 Dec;
PMID: 39649579
Eating disorders (ED) and obsessive-compulsive disorder (OCD) exhibit significant clinical and genetic overlap, yet their shared molecular mechanisms remain unclear. We conducted a transcriptomic investigation of the dorsolateral prefrontal cortex...
7.
Totty M, Juanes R, Bach S, Ameur L, Valentine M, Simons E, et al.
bioRxiv
. 2024 Oct;
PMID: 39463931
The amygdaloid complex mediates learning, memory, and emotions. Understanding the cellular and anatomical features that are specialized in the amygdala of primates versus other vertebrates requires a systematic, anatomically-resolved molecular...
8.
White J, Minto M, Willis C, Quach B, Han S, Tao R, et al.
Biol Psychiatry Glob Open Sci
. 2024 Oct;
4(6):100375.
PMID: 39399155
Background: Alcohol use disorder (AUD) has a profound public health impact. However, understanding of the molecular mechanisms that underlie the development and progression of AUD remains limited. Here, we investigated...
9.
Willis C, White J, Minto M, Quach B, Han S, Tao R, et al.
Mol Psychiatry
. 2024 Oct;
PMID: 39394458
Excessive alcohol consumption is a leading cause of preventable death worldwide. To improve understanding of neurobiological mechanisms associated with alcohol use disorder (AUD) in humans, we compared gene expression data...
10.
Kwon S, Parthiban S, Tippani M, Divecha H, Eagles N, Lobana J, et al.
GEN Biotechnol
. 2024 Sep;
2(5):399-417.
PMID: 39329069
Neuropathological lesions in the brains of individuals affected with neurodegenerative disorders are hypothesized to trigger molecular and cellular processes that disturb homeostasis of local microenvironments. Here, we applied the 10x...