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Amy Deep-Soboslay

Explore the profile of Amy Deep-Soboslay including associated specialties, affiliations and a list of published articles. Areas
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Citations 1281
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Recent Articles
1.
Breen M, Tao R, Yang A, Wang X, Amini P, de Los Santos M, et al.
medRxiv . 2024 Dec; PMID: 39649579
Eating disorders (ED) and obsessive-compulsive disorder (OCD) exhibit significant clinical and genetic overlap, yet their shared molecular mechanisms remain unclear. We conducted a transcriptomic investigation of the dorsolateral prefrontal cortex...
2.
White J, Minto M, Willis C, Quach B, Han S, Tao R, et al.
Biol Psychiatry Glob Open Sci . 2024 Oct; 4(6):100375. PMID: 39399155
Background: Alcohol use disorder (AUD) has a profound public health impact. However, understanding of the molecular mechanisms that underlie the development and progression of AUD remains limited. Here, we investigated...
3.
Willis C, White J, Minto M, Quach B, Han S, Tao R, et al.
Mol Psychiatry . 2024 Oct; PMID: 39394458
Excessive alcohol consumption is a leading cause of preventable death worldwide. To improve understanding of neurobiological mechanisms associated with alcohol use disorder (AUD) in humans, we compared gene expression data...
4.
Carnes M, Quach B, Zhou L, Han S, Tao R, Mandal M, et al.
Neuropsychopharmacology . 2024 Jun; 49(11):1749-1757. PMID: 38830989
Smoking is a leading cause of preventable morbidity and mortality. Smoking is heritable, and genome-wide association studies (GWASs) of smoking behaviors have identified hundreds of significant loci. Most GWAS-identified variants...
5.
Daskalakis N, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, et al.
Science . 2024 May; 384(6698):eadh3707. PMID: 38781393
The molecular pathology of stress-related disorders remains elusive. Our brain multiregion, multiomic study of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) included the central nucleus of the amygdala,...
6.
White J, Minto M, Willis C, Quach B, Han S, Tao R, et al.
medRxiv . 2024 Jan; PMID: 38293028
Background: Alcohol use disorder (AUD) has a profound public health impact. However, understanding of the molecular mechanisms underlying the development and progression of AUD remain limited. Here, we interrogate AUD-associated...
7.
Carnes M, Quach B, Zhou L, Han S, Tao R, Mandal M, et al.
medRxiv . 2023 Oct; PMID: 37790540
Smoking is a leading cause of preventable morbidity and mortality. Smoking is heritable, and genome-wide association studies (GWAS) of smoking behaviors have identified hundreds of significant loci. Most GWAS-identified variants...
8.
Iverson G, Jamshidi P, Fisher-Hubbard A, Deep-Soboslay A, Hyde T, Kleinman J, et al.
Front Neurol . 2023 Jul; 14:1143882. PMID: 37404944
Introduction: We examined postmortem brain tissue from men, over the age of 50, for chronic traumatic encephalopathy neuropathologic change (CTE-NC). We hypothesized that (i) a small percentage would have CTE-NC,...
9.
Sosnowski D, Jaffe A, Tao R, Deep-Soboslay A, Shu C, Sabunciyan S, et al.
Drug Alcohol Depend Rep . 2023 Feb; 3:100040. PMID: 36845993
Background: Although preclinical models reveal the neurobiological pathways altered through opioid abuse, comprehensive assessments of gene expression in human brain samples are needed. Moreover, less is known about gene expression...
10.
Benjamin K, Chen Q, Jaffe A, Stolz J, Collado-Torres L, Huuki-Myers L, et al.
Nat Neurosci . 2022 Nov; 25(11):1559-1568. PMID: 36319771
Most studies of gene expression in the brains of individuals with schizophrenia have focused on cortical regions, but subcortical nuclei such as the striatum are prominently implicated in the disease,...