Daniel R Weinberger
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Explore the profile of Daniel R Weinberger including associated specialties, affiliations and a list of published articles.
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495
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Recent Articles
1.
Zhou Y, Su Y, Yang Q, Li J, Hong Y, Gao T, et al.
bioRxiv
. 2025 Mar;
PMID: 40027814
Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis contribute to plasticity, learning and memory, but their evolutionary changes across species and specialized features in humans remain poorly understood....
2.
Zhou J, Luo C, Liu H, Heffel M, Straub R, Kleinman J, et al.
Cell Genom
. 2025 Feb;
5(3):100774.
PMID: 39986279
DNA methylation (DNAm) is a key epigenetic mark with essential roles in gene regulation, mammalian development, and human diseases. Single-cell technologies enable profiling DNAm at cytosines in individual cells, but...
3.
Chen X, Lu Y, Cue J, Han M, Nimgaonkar V, Weinberger D, et al.
Schizophrenia (Heidelb)
. 2025 Feb;
11(1):14.
PMID: 39910091
Many psychiatric disorders share genetic liabilities, but whether these shared liabilities can be utilized to classify and differentiate psychiatric disorders remains unclear. In this study, we use polygenic risk scores...
4.
Zhou J, Weinberger D, Han S
Sci Adv
. 2025 Jan;
11(1):eadn1870.
PMID: 39742481
DNA methylation (DNAm) is essential for brain development and function and potentially mediates the effects of genetic risk variants underlying brain disorders. We present INTERACT, a transformer-based deep learning model...
5.
Garcia-Marin L, Campos A, Diaz-Torres S, Rabinowitz J, Ceja Z, Mitchell B, et al.
Nat Genet
. 2024 Oct;
56(11):2333-2344.
PMID: 39433889
Subcortical brain structures are involved in developmental, psychiatric and neurological disorders. Here we performed genome-wide association studies meta-analyses of intracranial and nine subcortical brain volumes (brainstem, caudate nucleus, putamen, hippocampus,...
6.
Garcia-Marin L, Campos A, Diaz-Torres S, Rabinowitz J, Ceja Z, Mitchell B, et al.
medRxiv
. 2024 Oct;
PMID: 39371125
Subcortical brain structures are involved in developmental, psychiatric and neurological disorders. We performed GWAS meta-analyses of intracranial and nine subcortical brain volumes (brainstem, caudate nucleus, putamen, hippocampus, globus pallidus, thalamus,...
7.
Borcuk C, Parihar M, Sportelli L, Kleinman J, Shin J, Hyde T, et al.
Neuron
. 2024 Sep;
112(21):3551-3566.e6.
PMID: 39236717
The omnigenic model posits that genetic risk for traits with complex heritability involves cumulative effects of peripheral genes on mechanistic "core genes," suggesting that in a network of genes, those...
8.
Chen Q, Aguirre L, Liang G, Zhao H, Dong T, Borrego F, et al.
Mol Neurodegener
. 2024 Aug;
19(1):63.
PMID: 39210471
Background: The APOE gene is the strongest genetic risk factor for late-onset Alzheimer's Disease (LOAD). However, the gene regulatory mechanisms at this locus remain incompletely characterized. Methods: To identify novel...
9.
Mei F, Zhao C, Li S, Xue Z, Zhao Y, Xu Y, et al.
Nat Commun
. 2024 Aug;
15(1):7342.
PMID: 39187496
Acetylcholine regulates various cognitive functions through broad cholinergic innervation. However, specific cholinergic subpopulations, circuits and molecular mechanisms underlying recognition memory remain largely unknown. Here we show that Ngfr cholinergic neurons...
10.
Kim S, Seo S, Stein-OBrien G, Jaishankar A, Ogawa K, Micali N, et al.
Stem Cell Reports
. 2024 Aug;
19(9):1336-1350.
PMID: 39151428
Variability between human pluripotent stem cell (hPSC) lines remains a challenge and opportunity in biomedicine. In this study, hPSC lines from multiple donors were differentiated toward neuroectoderm and mesendoderm lineages....