Andrew E Jaffe
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Explore the profile of Andrew E Jaffe including associated specialties, affiliations and a list of published articles.
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131
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Recent Articles
1.
Craig G, Ramos L, Essig S, Eagles N, Jaffe A, Martinowich K, et al.
eNeuro
. 2024 Dec;
11(12).
PMID: 39632090
The medial frontal cortex (mFC) and locus ceruleus (LC) are two brain areas that have been implicated in a range of cognitive phenomena, such as attention, memory, and decision-making. Regulators...
2.
Gonzalez-Padilla D, Eagles N, Cano M, Pertea G, Jaffe A, Maynard K, et al.
bioRxiv
. 2024 Nov;
PMID: 39574597
Maternal smoking during pregnancy (MSDP) is associated with significant cognitive and behavioral effects on offspring. While neurodevelopmental outcomes have been studied for prenatal exposure to nicotine, the main psychoactive component...
3.
Craig G, Ramos L, Essig S, Eagles N, Jaffe A, Martinowich K, et al.
bioRxiv
. 2024 Aug;
PMID: 39091890
Deficits in attention are common across a range of neuropsychiatric disorders. A multitude of brain regions, including the frontal cortex (FC) and locus coeruleus (LC), have been implicated in attention....
4.
Carnes M, Quach B, Zhou L, Han S, Tao R, Mandal M, et al.
Neuropsychopharmacology
. 2024 Jun;
49(11):1749-1757.
PMID: 38830989
Smoking is a leading cause of preventable morbidity and mortality. Smoking is heritable, and genome-wide association studies (GWASs) of smoking behaviors have identified hundreds of significant loci. Most GWAS-identified variants...
5.
Wen C, Margolis M, Dai R, Zhang P, Przytycki P, Vo D, et al.
Science
. 2024 May;
384(6698):eadh0829.
PMID: 38781368
Neuropsychiatric genome-wide association studies (GWASs), including those for autism spectrum disorder and schizophrenia, show strong enrichment for regulatory elements in the developing brain. However, prioritizing risk genes and mechanisms is...
6.
Benjamin K, Chen Q, Eagles N, Huuki-Myers L, Collado-Torres L, Stolz J, et al.
Nat Neurosci
. 2024 May;
27(6):1064-1074.
PMID: 38769152
Ancestral differences in genomic variation affect the regulation of gene expression; however, most gene expression studies have been limited to European ancestry samples or adjusted to identify ancestry-independent associations. Here,...
7.
Tippani M, Divecha H, Catallini 2nd J, Kwon S, Weber L, Spangler A, et al.
Biol Imaging
. 2024 Mar;
3:e23.
PMID: 38510173
Spatially resolved transcriptomics (SRT) is a growing field that links gene expression to anatomical context. SRT approaches that use next-generation sequencing (NGS) combine RNA sequencing with histological or fluorescent imaging...
8.
Rodriguez L, Tran M, Garcia-Flores R, Oh S, Phillips 3rd R, Pattie E, et al.
Transl Psychiatry
. 2024 Jan;
14(1):52.
PMID: 38263132
The lateral septum (LS), a GABAergic structure located in the basal forebrain, is implicated in social behavior, learning, and memory. We previously demonstrated that expression of tropomyosin kinase receptor B...
9.
Carnes M, Quach B, Zhou L, Han S, Tao R, Mandal M, et al.
medRxiv
. 2023 Oct;
PMID: 37790540
Smoking is a leading cause of preventable morbidity and mortality. Smoking is heritable, and genome-wide association studies (GWAS) of smoking behaviors have identified hundreds of significant loci. Most GWAS-identified variants...
10.
Eagles N, Wilton R, Jaffe A, Collado-Torres L
BMC Bioinformatics
. 2023 Sep;
24(1):340.
PMID: 37704947
Background: Bisulfite sequencing is a powerful tool for profiling genomic methylation, an epigenetic modification critical in the understanding of cancer, psychiatric disorders, and many other conditions. Raw data generated by...