Joe R Delaney
Overview
Explore the profile of Joe R Delaney including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
2050
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Recent Articles
1.
Rees A, Villamor E, Evans D, Gooz M, Fallon C, Mina-Abouda M, et al.
Genes (Basel)
. 2025 Jan;
16(1.
PMID: 39858588
Background/objectives: All 11 metallothionein protein-coding genes are located on human chromosome 16q13. It is unique among human genetics to have an entire pathway's genes clustered in a short chromosomal region....
2.
Williams I, OMalley M, DeHart H, Walker B, Ulhaskumar V, Jothirajah P, et al.
Cancer Res Commun
. 2025 Jan;
5(2):253-266.
PMID: 39831777
We show that HSF1 and MYC genes are co-amplified in more than 30% of HGSOC and demonstrate that HSF1 and MYC functionally cooperate to drive the growth of HGSOC cells....
3.
Min K, Choi K, Mun H, Ko S, Lee J, Sagum C, et al.
J Cell Sci
. 2024 Sep;
137(21).
PMID: 39308343
Argonaute (AGO), a component of RNA-induced silencing complexes (RISCs), is a representative RNA-binding protein (RBP) known to bind with mature microRNAs (miRNAs) and is directly involved in post-transcriptional gene silencing....
4.
Vaena S, Romeo M, Mina-Abouda M, Funk E, Fullbright G, Long D, et al.
Cell Cycle
. 2024 Sep;
:1-21.
PMID: 39299930
Hydroxychloroquine (HCQ) and chloroquine are repurposed drugs known to disrupt autophagy, a molecular recycling pathway essential for tumor cell survival, chemotherapeutic resistance, and stemness. We pursued a multi-omic strategy in...
5.
Blackman A, Rees A, Bowers R, Jones C, Vaena S, Clark M, et al.
Cancer Res Commun
. 2024 Sep;
4(9):2525-2538.
PMID: 39225558
Significance: Mouse models using transgenes which generate spontaneous cancers are essential tools to examine the etiology of human diseases. Here, the first Myc-driven spontaneous model is described as a valid...
6.
Gensemer C, Beck T, Guo L, Petrucci T, Morningstar J, Kornblau I, et al.
Res Sq
. 2024 Jul;
PMID: 38947032
Hypermobile Ehlers-Danlos syndrome (hEDS) is a common heritable connective tissue disorder that lacks a known genetic etiology. To identify genetic contributions to hEDS, whole exome sequencing was performed on families...
7.
Williams I, DeHart H, OMalley M, Walker B, Ulhaskumar V, Ray H, et al.
bioRxiv
. 2024 Jun;
PMID: 38915574
Ovarian cancer is a deadly female cancer with high rates of recurrence. The primary treatment strategy for patients is platinum-based therapy regimens that almost universally develop resistance. Consequently, new therapeutic...
8.
White-Gilbertson S, Lu P, Saatci O, Sahin O, Delaney J, Ogretmen B, et al.
J Biol Chem
. 2024 Mar;
300(4):107136.
PMID: 38447798
Polyploid giant cancer cells (PGCC) are frequently detected in tumors and are increasingly recognized for their roles in chromosomal instability and associated genome evolution that leads to cancer recurrence. We...
9.
Blackman A, Rees A, Bowers R, Jones C, Vaena S, Clark M, et al.
bioRxiv
. 2024 Feb;
PMID: 38352443
Genetically engineered mouse models (GEMM) have fundamentally changed how ovarian cancer etiology, early detection, and treatment is understood. However, previous GEMMs of high-grade serous ovarian cancer (HGSOC) have had to...
10.
Brobbey C, Yin S, Liu L, Ball L, Howe P, Delaney J, et al.
Sci Rep
. 2023 Jul;
13(1):10752.
PMID: 37400460
Protein arginine methyltransferase 5 (PRMT5) catalyzes mono-methylation and symmetric di-methylation on arginine residues and has emerged as a potential antitumor target with inhibitors being tested in clinical trials. However, it...