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Brian K Kennedy

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Articles 227
Citations 13517
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Recent Articles
1.
Woods T, Palmarini N, Corner L, Barzilai N, Maier A, Sagner M, et al.
Nat Med . 2025 Mar; PMID: 40075229
No abstract available.
2.
Tay J, Wang W, Guan L, Dorajoo R, Khor C, Feng L, et al.
J Gerontol A Biol Sci Med Sci . 2025 Jan; PMID: 39869450
Deoxyribonucleic acid (DNA) methylation (DNAm) clocks estimate biological age according to DNA methylation. This study investigated the associations between measures of physical function and physical performance and ten DNAm clocks...
3.
Lu J, Wang W, Soh J, Sandalova E, Lim Z, Seetharaman S, et al.
Geroscience . 2025 Jan; PMID: 39825169
Ageing is the primary driver of age-associated chronic diseases and conditions. Asian populations have traditionally been underrepresented in studies understanding age-related diseases. Thus, the Ageing BIOmarker Study in Singaporeans (ABIOS)...
4.
Huang H, Chen Y, Xu W, Cao L, Qian K, Bischof E, et al.
Cell Metab . 2024 Dec; 37(1):34-58. PMID: 39657675
Chronological age is a crucial risk factor for diseases and disabilities among older adults. However, individuals of the same chronological age often exhibit divergent biological aging states, resulting in distinct...
5.
Fuellen G, Kulaga A, Lobentanzer S, Unfried M, Avelar R, Palmer D, et al.
Ageing Res Rev . 2024 Dec; 104:102617. PMID: 39643211
The field of aging and longevity research is overwhelmed by vast amounts of data, calling for the use of Artificial Intelligence (AI), including Large Language Models (LLMs), for the evaluation...
6.
Pabis K, Barardo D, Gruber J, Sirbu O, Malavolta M, Selvarajoo K, et al.
Ageing Res Rev . 2024 Sep; 101:102512. PMID: 39332712
Although lifespan extension remains the gold standard for assessing interventions proposed to impact the biology of aging, there are important limitations to this approach. Our reanalysis of lifespan studies from...
7.
Ravikrishnan A, Wijaya I, Png E, Chng K, Ho E, Ng A, et al.
Nat Commun . 2024 Sep; 15(1):7751. PMID: 39237540
While rapid demographic changes in Asia are driving the incidence of chronic aging-related diseases, the limited availability of high-quality in vivo data hampers our ability to understand complex multi-factorial contributions,...
8.
Navakkode S, Kennedy B
Front Aging Neurosci . 2024 Aug; 16:1428244. PMID: 39161341
Ageing is characterized by a gradual decline in the efficiency of physiological functions and increased vulnerability to diseases. Ageing affects the entire body, including physical, mental, and social well-being, but...
9.
Blank H, Hammer S, Boatright L, Roberts C, Heyden K, Nagarajan A, et al.
Life Sci Alliance . 2024 Jul; 7(10). PMID: 39043420
Folate is a vitamin required for cell growth and is present in fortified foods in the form of folic acid to prevent congenital abnormalities. The impact of low-folate status on...
10.
Robert M, Kennedy B, Crasta K
Redox Biol . 2024 Jun; 74:103228. PMID: 38865902
Therapy-induced senescent tumor cells have emerged as significant drivers of tumor recurrence and disease relapse. Interestingly, reactive oxygen species (ROS) production and its associated redox signaling networks are intertwined with...