Jisca Majolee
Overview
Explore the profile of Jisca Majolee including associated specialties, affiliations and a list of published articles.
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13
Citations
145
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Recent Articles
1.
Woutersen D, Majolee J, den Hertog J
Methods Mol Biol
. 2023 Dec;
2743:93-110.
PMID: 38147210
The zebrafish is an ideal model for functional analysis of genes at the molecular, protein, cell, organ, and organism levels. We have used zebrafish to analyze the function of members...
2.
Podieh F, Wensveen R, Overboom M, Abbas L, Majolee J, Hordijk P
J Biol Chem
. 2023 Mar;
299(4):104593.
PMID: 36894017
Endothelial monolayer permeability is regulated by actin dynamics and vesicular traffic. Recently, ubiquitination was also implicated in the integrity of quiescent endothelium, as it differentially controls the localization and stability...
3.
Manz X, Szulcek R, Pan X, Symersky P, Dickhoff C, Majolee J, et al.
Am J Respir Crit Care Med
. 2022 Jan;
205(7):806-818.
PMID: 35081007
von Willebrand factor (vWF) mediates platelet adhesion during thrombosis. While chronic thromboembolic pulmonary hypertension (CTEPH) is associated with increased plasma levels of vWF, the role of this protein in CTEPH...
4.
Mosaddeghzadeh N, Kazemein Jasemi N, Majolee J, Zhang S, Hordijk P, Dvorsky R, et al.
Int J Mol Sci
. 2021 Nov;
22(22).
PMID: 34830380
Three decades of research have documented the spatiotemporal dynamics of RHO family GTPase membrane extraction regulated by guanine nucleotide dissociation inhibitors (GDIs), but the interplay of the kinetic mechanism and...
5.
Majolee J, Podieh F, Hordijk P, Kovacevic I
PLoS One
. 2021 Jul;
16(7):e0254386.
PMID: 34252134
Signaling by the Rho GTPase Rac1 is key to the regulation of cytoskeletal dynamics, cell spreading and adhesion. It is widely accepted that the inactive form of Rac1 is bound...
6.
Bogunovic N, Meekel J, Majolee J, Hekhuis M, Pyszkowski J, Jockenhovel S, et al.
J Endovasc Ther
. 2021 Apr;
28(4):604-613.
PMID: 33902345
Introduction: Abdominal aortic aneurysms (AAAs) are associated with overall high mortality in case of rupture. Since the pathophysiology is unclear, no adequate pharmacological therapy exists. Smooth muscle cells (SMCs) dysfunction...
7.
van der Wijk A, Georgakopoulou T, Majolee J, van Bezu J, van der Stoel M, van Het Hof B, et al.
Acta Neuropathol Commun
. 2020 Nov;
8(1):195.
PMID: 33203478
Considering its intolerance to ischemia, it is of critical importance for the brain to efficiently process microvascular occlusions and maintain tissue perfusion. In addition to collateral microvascular flow and enzymatic...
8.
Majolee J, Kovacevic I, Hordijk P
J Cell Sci
. 2019 Sep;
132(17).
PMID: 31488505
Endothelial cell-cell contacts are essential for vascular integrity and physiology, protecting tissues and organs from edema and uncontrolled invasion of inflammatory cells. The vascular endothelial barrier is dynamic, but its...
9.
CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity
Majolee J, Pronk M, Jim K, van Bezu J, van der Sar A, Hordijk P, et al.
Sci Rep
. 2019 Jun;
9(1):8131.
PMID: 31148579
RhoGTPases regulate cytoskeletal dynamics, migration and cell-cell adhesion in endothelial cells. Besides regulation at the level of guanine nucleotide binding, they also undergo post-translational modifications, for example ubiquitination. RhoGTPases are...
10.
Dekker N, van Leeuwen A, van Strien W, Majolee J, Szulcek R, Vonk A, et al.
Crit Care
. 2019 Apr;
23(1):117.
PMID: 30975180
Background: Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier function...