Igor Kovacevic
Overview
Explore the profile of Igor Kovacevic including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
415
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Recent Articles
1.
Vasilijevic J, Kovacevic I, Polovina S, Dacic-Krnjaja B, Kalezic T, Miletic S, et al.
J Pers Med
. 2024 Jul;
14(7).
PMID: 39063950
(1) Background: This study aims to evaluate retinal perfusion by optical coherence tomography angiography (OCTA) in pediatric patients with type 1 diabetes mellitus (T1D) without diabetic retinopathy (DR). (2) Methods:...
2.
Kovacevic I, Schmidt P, Kowalski A, Helms B, van de Lest C, Kluttig A, et al.
Cell Commun Signal
. 2024 Jun;
22(1):304.
PMID: 38831326
Elevated concentrations of palmitate in serum of obese individuals can impair endothelial function, contributing to development of cardiovascular disease. Although several molecular mechanisms of palmitate-induced endothelial dysfunction have been proposed,...
3.
Vasilijevic J, Peric S, Basta I, Kovacevic I, Maric G, Avram N, et al.
Eur J Ophthalmol
. 2024 Apr;
35(1):262-268.
PMID: 38644803
Background: The aim of the study was to detect the changes in retinal and choroidal vasculature via optical coherence tomography angiography (OCTA) by comparing the quantitative OCTA parameters in patients...
4.
Nisic F, Pidro A, Lepara O, Fajkic A, Miokovic A, Suljic E, et al.
Rom J Ophthalmol
. 2022 Nov;
66(3):265-270.
PMID: 36349176
This study aimed to determine the intravitreal concentration of VEGF in eyes with PDR and to evaluate the effects of previous PRP on its level. It was a cross-sectional study...
5.
Jeremic M, Kovacevic I, Vasilijevic J, Kalezic T, Bozic M
Indian J Ophthalmol
. 2022 Oct;
70(10):3607-3609.
PMID: 36190055
Purpose: The study was conducted to determine the ocular pulse amplitude (OPA) changes, measured with a dynamic contour tonometer (DCT), after surgical retinal detachment repair. Methods: This was a prospective...
6.
Majolee J, Podieh F, Hordijk P, Kovacevic I
PLoS One
. 2021 Jul;
16(7):e0254386.
PMID: 34252134
Signaling by the Rho GTPase Rac1 is key to the regulation of cytoskeletal dynamics, cell spreading and adhesion. It is widely accepted that the inactive form of Rac1 is bound...
7.
Tan J, van der Stoel M, van den Berg M, van Loon N, Moeton M, Scholl E, et al.
Cell Rep
. 2020 Aug;
32(5):107944.
PMID: 32755570
The endothelial monolayer forms a barrier between the lumen of blood vessels and the underlying tissues. Stable VE-cadherin-based adherens junctions are essential for maintaining this barrier, whereas their remodeling is...
8.
Majolee J, Kovacevic I, Hordijk P
J Cell Sci
. 2019 Sep;
132(17).
PMID: 31488505
Endothelial cell-cell contacts are essential for vascular integrity and physiology, protecting tissues and organs from edema and uncontrolled invasion of inflammatory cells. The vascular endothelial barrier is dynamic, but its...
9.
CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity
Majolee J, Pronk M, Jim K, van Bezu J, van der Sar A, Hordijk P, et al.
Sci Rep
. 2019 Jun;
9(1):8131.
PMID: 31148579
RhoGTPases regulate cytoskeletal dynamics, migration and cell-cell adhesion in endothelial cells. Besides regulation at the level of guanine nucleotide binding, they also undergo post-translational modifications, for example ubiquitination. RhoGTPases are...
10.
Pronk M, Majolee J, Loregger A, van Bezu J, Zelcer N, Hordijk P, et al.
Mol Biol Cell
. 2019 Jan;
30(5):607-621.
PMID: 30601691
Rho GTPases control both the actin cytoskeleton and adherens junction stability and are recognized as essential regulators of endothelial barrier function. They act as molecular switches and are primarily regulated...