Jin D Chung
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Explore the profile of Jin D Chung including associated specialties, affiliations and a list of published articles.
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10
Citations
158
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Recent Articles
1.
Chung J, Porrello E, Lynch G
Free Radic Biol Med
. 2024 Nov;
227():52-63.
PMID: 39581389
Skeletal muscle has a high regenerative capacity due to its resident adult muscle stem cells (MuSCs), which can repair damaged tissue by forming myofibres de novo. Stem cell dependent regeneration...
2.
McNamara J, Parker B, Voges H, Mehdiabadi N, Bolk F, Ahmad F, et al.
Nat Cardiovasc Res
. 2024 Aug;
2(2):159-173.
PMID: 39196058
Muscle contraction is driven by the molecular machinery of the sarcomere. As phosphorylation is a critical regulator of muscle function, the identification of regulatory kinases is important for understanding sarcomere...
3.
Swiderski K, Chan A, Herold M, Kueh A, Chung J, Hardee J, et al.
Dis Model Mech
. 2024 Apr;
17(4).
PMID: 38602028
Duchenne muscular dystrophy (DMD) is a devastating monogenic skeletal muscle-wasting disorder. Although many pharmacological and genetic interventions have been reported in preclinical studies, few have progressed to clinical trials with...
4.
Blazev R, Carl C, Ng Y, Molendijk J, Voldstedlund C, Zhao Y, et al.
Cell Metab
. 2022 Jul;
34(10):1561-1577.e9.
PMID: 35882232
Exercise induces signaling networks to improve muscle function and confer health benefits. To identify divergent and common signaling networks during and after different exercise modalities, we performed a phosphoproteomic analysis...
5.
Ovens A, Gee Y, Ling N, Yu D, Hardee J, Chung J, et al.
Biochem J
. 2022 May;
479(11):1181-1204.
PMID: 35552369
The AMP-activated protein kinase (AMPK) αβγ heterotrimer is a primary cellular energy sensor and central regulator of energy homeostasis. Activating skeletal muscle AMPK with small molecule drugs improves glucose uptake...
6.
Alves F, Kysenius K, Caldow M, Hardee J, Chung J, Trieu J, et al.
J Cachexia Sarcopenia Muscle
. 2022 Mar;
13(3):1541-1553.
PMID: 35249268
Background: Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular...
7.
Swiderski K, Read S, Chan A, Chung J, Trieu J, Naim T, et al.
Nutrients
. 2021 Dec;
13(12).
PMID: 34960110
Gastrointestinal (GI) dysfunction is an important, yet understudied condition associated with Duchenne muscular dystrophy (DMD), with patients reporting bloating, diarrhea, and general discomfort, contributing to a reduced quality of life....
8.
Tian L, Jabbari J, Thijssen R, Gouil Q, Amarasinghe S, Voogd O, et al.
Genome Biol
. 2021 Nov;
22(1):310.
PMID: 34763716
A modified Chromium 10x droplet-based protocol that subsamples cells for both short-read and long-read (nanopore) sequencing together with a new computational pipeline (FLAMES) is developed to enable isoform discovery, splicing...
9.
Hardee J, Martins K, Miotto P, Ryall J, Gehrig S, Reljic B, et al.
Mol Metab
. 2020 Dec;
45:101157.
PMID: 33359740
Objectives: Preferential damage to fast, glycolytic myofibers is common in many muscle-wasting diseases, including Duchenne muscular dystrophy (DMD). Promoting an oxidative phenotype could protect muscles from damage and ameliorate the...
10.
Nguyen J, Chung J, Lynch G, Ryall J
Front Cell Dev Biol
. 2019 Nov;
7:254.
PMID: 31737625
Skeletal muscle has a remarkable capacity to regenerate following injury, a property conferred by a resident population of muscle stem cells (MuSCs). In response to injury, MuSCs must double their...