Rene Koopman
Overview
Explore the profile of Rene Koopman including associated specialties, affiliations and a list of published articles.
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Articles
87
Citations
2919
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Recent Articles
1.
Wittholz K, Bongetti A, Fetterplace K, Caldow M, Karahalios A, de Souza D, et al.
JPEN J Parenter Enteral Nutr
. 2024 Mar;
48(4):421-428.
PMID: 38522007
Background: During critical illness skeletal muscle wasting occurs rapidly. Although beta-hydroxy-beta-methylbutyrate (HMB) is a potential treatment to attenuate this process, the plasma appearance and muscle concentration is uncertain. Methods: This...
2.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee A, et al.
Nat Metab
. 2024 Mar;
6(3):433-447.
PMID: 38504132
Mitochondrial dysfunction and low nicotinamide adenine dinucleotide (NAD) levels are hallmarks of skeletal muscle ageing and sarcopenia, but it is unclear whether these defects result from local changes or can...
3.
Wittholz K, Fetterplace K, Karahalios A, Abdelhamid Y, Beach L, Read D, et al.
JPEN J Parenter Enteral Nutr
. 2023 Jun;
47(8):983-992.
PMID: 37357015
Background: Beta-hydroxy-beta-methylbutyrate (HMB) is a nutrition supplement that may attenuate muscle wasting from critical illness. This trial aimed to determine feasibility of administering a blinded nutrition supplement in the intensive...
4.
Alves F, Ayton S, Bush A, Lynch G, Koopman R
J Gerontol A Biol Sci Med Sci
. 2022 Jul;
78(1):16-24.
PMID: 35869751
Sarcopenia is an age-related condition of slow, progressive loss of muscle mass and strength, which contributes to frailty, increased risk of hospitalization and mortality, and increased health care costs. The...
5.
Xiao D, Caldow M, Kim H, Blazev R, Koopman R, Manandi D, et al.
iScience
. 2022 Jun;
25(6):104489.
PMID: 35721465
Myogenesis is governed by signaling networks that are tightly regulated in a time-dependent manner. Although different protein kinases have been identified, knowledge of the global signaling networks and their downstream...
6.
Alves F, Kysenius K, Caldow M, Hardee J, Chung J, Trieu J, et al.
J Cachexia Sarcopenia Muscle
. 2022 Mar;
13(3):1541-1553.
PMID: 35249268
Background: Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular...
7.
Van Ancum J, Tuttle C, Koopman R, Pijnappels M, Meskers C, Paul S, et al.
Eur Geriatr Med
. 2022 Mar;
13(3):623-632.
PMID: 35235196
Purpose: Albumin and C-reactive protein (CRP) are non-specific markers of inflammation, which could affect muscle tissue during acute hospitalization. We investigated the association between albumin and CRP during acute hospitalization...
8.
Wittholz K, Fetterplace K, Abdelhamid Y, Presneill J, Beach L, Thomson B, et al.
Pilot Feasibility Stud
. 2022 Feb;
8(1):21.
PMID: 35101139
Background: There are no therapies proven to diminish the muscle wasting that occurs in patients after major trauma who are admitted to the intensive care unit (ICU). β-Hydroxy-β-methylbutyrate (HMB) is...
9.
Alves F, Caldow M, Helman S, Ayton S, Bush A, Lynch G, et al.
Biochim Biophys Acta Gen Subj
. 2022 Jan;
1866(3):130082.
PMID: 34995689
No abstract available.
10.
Swiderski K, Read S, Chan A, Chung J, Trieu J, Naim T, et al.
Nutrients
. 2021 Dec;
13(12).
PMID: 34960110
Gastrointestinal (GI) dysfunction is an important, yet understudied condition associated with Duchenne muscular dystrophy (DMD), with patients reporting bloating, diarrhea, and general discomfort, contributing to a reduced quality of life....