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Jim W Neal

Explore the profile of Jim W Neal including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 389
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Recent Articles
1.
Bedoui Y, Lebeau G, Guillot X, Dargai F, Guiraud P, Neal J, et al.
J Neuroimmune Pharmacol . 2020 Sep; 15(4):838-851. PMID: 32964324
In contrast to the significant advances in our understanding of the mesenchymal stem cell (MSC) populations in bone marrow (BM), little is known about the MSCs that are resident in...
2.
Bedoui Y, Neal J, Gasque P
J Neuroimmune Pharmacol . 2018 Jun; 13(3):309-329. PMID: 29909495
An effective protective inflammatory response in the brain is crucial for the clearance of pathogens (e.g. microbes, amyloid fibrils, prion) and should be closely regulated. However, the CNS seems to...
3.
Hoarau J, Krejbich-Trotot P, Jaffar-Bandjee M, Das T, Thon-Hon G, Kumar S, et al.
CNS Neurol Disord Drug Targets . 2010 Dec; 10(1):25-43. PMID: 21143144
Innate immunity is an arsenal of molecules and receptors expressed by professional phagocytes, glial cells and neurons and involved in host defence and clearance of toxic and dangerous cell debris....
4.
Griffiths M, Neal J, Fontaine M, Das T, Gasque P
J Immunol . 2009 Mar; 182(7):4368-77. PMID: 19299737
The CNS innate immune response is a "double-edged sword" representing a fine balance between protective antipathogen responses and detrimental neurocytotoxic effects. Hence, it is important to identify the key regulatory...
5.
Dhingra N, Gajdasty A, Neal J, Mukherjee A, Lane C
Br J Ophthalmol . 2007 Jan; 91(6):794-6. PMID: 17229804
Aims: To report a new technique of tissue preparation, using a marginal strip, after the excision of eyelid basal cell carcinomas (BCCs) and to report the long-term results of BCCs...
6.
Nicoll J, Barton E, Boche D, Neal J, Ferrer I, Thompson P, et al.
J Neuropathol Exp Neurol . 2006 Nov; 65(11):1040-8. PMID: 17086100
Neuropathologic examination of 3 patients with Alzheimer disease in the Elan Pharmaceuticals trial using antibodies specific for different Abeta species showed in one case, 4 months after the immunization, evidence...
7.
Canova C, Neal J, Gasque P
J Neuroinflammation . 2006 Sep; 3:22. PMID: 16948860
Background: In meningitis, the cerebrospinal fluid contains high levels of innate immune molecules (e.g. complement) which are essential to ward off the infectious challenge and to promote the infiltration of...
8.
Elward K, Griffiths M, Mizuno M, Harris C, Neal J, Morgan B, et al.
J Biol Chem . 2005 Aug; 280(43):36342-54. PMID: 16087667
Complement is the canonical innate immune system involved in host defense and tissue repair with the clearance of cell debris. In contrast to the robust armory mounted against microbial nonself-pathogens,...
9.
van Beek J, van Meurs M, t Hart B, Brok H, Neal J, Chatagner A, et al.
J Immunol . 2005 Feb; 174(4):2353-65. PMID: 15699172
There is compelling evidence that a unique innate immune response in the CNS plays a critical role in host defense and clearance of toxic cell debris. Although complement has been...
10.
Francis K, van Beek J, Canova C, Neal J, Gasque P
Expert Rev Mol Med . 2003 Oct; 5(15):1-19. PMID: 14585169
The complement inflammatory cascade is an essential component of the phylogenetically ancient innate immune response and is crucial to our natural ability to ward off infection. Complement is involved in...