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B Paul Morgan

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Articles 242
Citations 7396
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Recent Articles
1.
Reed R, Zelek W, Morgan B, Whelehan G, Lockhart S, ORahilly S, et al.
Am J Physiol Endocrinol Metab . 2025 Mar; PMID: 40047170
Populations of Black African (BA) ancestry are disproportionately affected by cardiometabolic diseases, possibly due to dysregulation of the complement system. This study aimed to determine 1) relationships between fasting complement...
2.
Carter-Cusack D, Huang S, Keshvari S, Patkar O, Sehgal A, Allavena R, et al.
PLoS Genet . 2025 Jan; 21(1):e1011525. PMID: 39869647
Adaptation to existence outside the womb is a key event in the life of a mammal. The absence of macrophages in rats with a homozygous mutation in the colony-stimulating factor...
3.
Daskoulidou N, Carpanini S, Zelek W, Morgan B
Curr Top Behav Neurosci . 2025 Jan; PMID: 39849280
No abstract available.
4.
Daskoulidou N, Carpanini S, Zelek W, Morgan B
Curr Top Behav Neurosci . 2024 Oct; PMID: 39455500
Complement is a critical component of innate immunity, evolved to defend against pathogens and clear toxic debris ranging from dead and dying cells to immune complexes. These roles make complement...
5.
Zelek W, Bevan R, Nimmo J, Dewilde M, De Strooper B, Morgan B, et al.
Brain . 2024 Aug; 148(3):941-954. PMID: 39215579
Complement activation is implicated in driving brain inflammation, self-cell damage and progression of injury in Alzheimer's disease and other neurodegenerative diseases. Here, we investigate the impact of brain delivery of...
6.
Nimmo J, Byrne R, Daskoulidou N, Watkins L, Carpanini S, Zelek W, et al.
Clin Sci (Lond) . 2024 Mar; 138(6):387-412. PMID: 38505993
Complement is an important component of innate immune defence against pathogens and crucial for efficient immune complex disposal. These core protective activities are dependent in large part on properly regulated...
7.
Baillie K, Davies H, Keat S, Ladell K, Miners K, Jones S, et al.
Med . 2024 Feb; 5(3):239-253.e5. PMID: 38359836
Background: Long COVID encompasses a heterogeneous set of ongoing symptoms that affect many individuals after recovery from infection with SARS-CoV-2. The underlying biological mechanisms nonetheless remain obscure, precluding accurate diagnosis...
8.
Karbian N, Eshed-Eisenbach Y, Zeibak M, Tabib A, Sukhanov N, Vainshtein A, et al.
J Neuroinflammation . 2023 Oct; 20(1):245. PMID: 37875972
Background: Homozygous CD59-deficient patients manifest with recurrent peripheral neuropathy resembling Guillain-Barré syndrome (GBS), hemolytic anemia and recurrent strokes. Variable mutations in CD59 leading to loss of function have been described...
9.
Bowen E, Hurcombe J, Barrington F, Keir L, Farmer L, Wherlock M, et al.
Med . 2023 Oct; 4(11):761-777.e8. PMID: 37863058
Background: Shiga toxin (Stx)-producing Escherichia coli hemolytic uremic syndrome (STEC-HUS) is the leading cause of acute kidney injury in children, with an associated mortality of up to 5%. The mechanisms...
10.
Kamegai N, Kim H, Suzuki Y, Fukui S, Kojima H, Maruyama S, et al.
Clin Exp Immunol . 2023 Aug; 214(2):209-218. PMID: 37549240
Peritonitis and the resulting peritoneal injuries are common problems that prevent long-term peritoneal dialysis (PD) therapy in patients with end-stage kidney diseases. Previously, we have analyzed the relationship between the...