Herbert P M Brok
Overview
Explore the profile of Herbert P M Brok including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
310
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bakker J, Uilenreef J, Pelt E, Brok H, Remarque E, Langermans J
BMC Vet Res
. 2013 Jun;
9:113.
PMID: 23758836
Background: Handling of common marmoset (Callithrix jacchus) usually requires chemical restraint. Ketamine has been associated with muscle damage in primates, while common marmosets, compared to other primates, additionally display an...
2.
Jagessar S, Kap Y, Heijmans N, van Driel N, van Straalen L, Bajramovic J, et al.
J Neuropathol Exp Neurol
. 2010 May;
69(4):372-85.
PMID: 20448482
Experimental autoimmune encephalomyelitis in the neotropical primate common marmoset (Callithrix jacchus) is a relevant autoimmune animal model of multiple sclerosis. T cells specific for peptide 34 to 56 of myelin/oligodendrocyte...
3.
Kap Y, van Meurs M, van Driel N, Koopman G, Melief M, Brok H, et al.
J Histochem Cytochem
. 2009 Sep;
57(12):1159-67.
PMID: 19729671
Non-human primates (NHPs) offer valuable animal models for basic research into human diseases and for the preclinical validation of new therapeutics. Detailed in situ examination of the involved cell types...
4.
Bajramovic J, Brok H, Ouwerling B, Jagessar S, van Straalen L, Kondova I, et al.
Eur J Immunol
. 2008 Apr;
38(5):1452-64.
PMID: 18412169
Oligodendrocyte-specific protein (OSP) is a candidate autoantigen in the development of multiple sclerosis (MS). We evaluated the potential of OSP to induce EAE in rhesus monkeys, an out bred animal...
5.
Kap Y, Smith P, Jagessar S, Remarque E, Blezer E, Strijkers G, et al.
J Immunol
. 2008 Jan;
180(3):1326-37.
PMID: 18209026
The recombinant human (rh) myelin/oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) model in the common marmoset is characterized by 100% disease incidence, a chronic disease course, and a variable time...
6.
Brok H, Boven L, van Meurs M, Kerlero de Rosbo N, Celebi-Paul L, Kap Y, et al.
J Neuroimmunol
. 2006 Nov;
182(1-2):135-52.
PMID: 17126916
Rhesus monkeys immunized with MOG(34-56), a dominant T-cell epitope from myelin/oligodendrocyte glycoprotein, develop an acute neurological disease resembling acute disseminated encephalomyelitis (ADEM) in humans. The typical large demyelinated lesions and...
7.
Blezer E, Bauer J, Brok H, Nicolay K, t Hart B
NMR Biomed
. 2006 Sep;
20(2):90-103.
PMID: 16948176
Experimental autoimmune encephalomyelitis (EAE) induced with recombinant human myelin/oligodendrocyte glycoprotein in the common marmoset is a useful preclinical model of multiple sclerosis in which white matter lesions can be well...
8.
Doxiadis G, van der Wiel M, Brok H, de Groot N, Otting N, t Hart B, et al.
Proc Natl Acad Sci U S A
. 2006 Apr;
103(15):5864-8.
PMID: 16581907
The common marmoset (Callithrix jacchus), a New World monkey species with a limited MHC class II repertoire, is highly susceptible to certain bacterial infections. Genomic analysis of exon 2 sequences...
9.
t Hart B, Brok H, Remarque E, Benson J, Treacy G, Amor S, et al.
J Immunol
. 2005 Sep;
175(7):4761-8.
PMID: 16177124
IL-12p40 is a shared subunit of two cytokines with overlapping activities in the induction of autoreactive Th1 cells and therefore a potential target of therapy in Th1-mediated diseases. We have...
10.
t Hart B, Bauer J, Brok H, Amor S
J Neuroimmunol
. 2005 Jul;
168(1-2):1-12.
PMID: 16023737
Despite years of intensive research into multiple sclerosis (MS) scientists have not yet succeeded in developing an absolute therapy for the treatment of this disabling disease of the human central...