Jill P Mesirov
Overview
Explore the profile of Jill P Mesirov including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
128
Citations
82678
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Do M, Wu C, Sonavane P, Juarez E, Adams S, Ross J, et al.
Mol Cancer Ther
. 2021 Oct;
21(1):113-124.
PMID: 34667113
Although WNT signaling is frequently dysregulated in solid tumors, drugging this pathway has been challenging due to off-tumor effects. Current clinical pan-WNT inhibitors are nonspecific and lead to adverse effects,...
22.
Banerjee S, Yoon H, Ting S, Tang C, Yebra M, Wenzel A, et al.
Mol Cancer Ther
. 2021 Aug;
20(10):2035-2048.
PMID: 34376580
Gastrointestinal stromal tumor (GIST) is commonly driven by oncogenic mutations that are effectively targeted by imatinib (IM), a tyrosine kinase inhibitor (TKI). However, IM does not cure GIST, and adjuvant...
23.
Sharma A, de la Torre J, IJzerman N, Sutton T, Zhao B, Khan T, et al.
Clin Cancer Res
. 2021 Jul;
27(19):5334-5342.
PMID: 34326133
Purpose: Gastrointestinal stromal tumors (GIST) commonly arise in different regions of the stomach and are driven by various mutations (most often in KIT, PDGFRA, and SDHx). We hypothesized that the...
24.
Chen K, Ozturk K, Liefeld T, Reich M, Mesirov J, Carter H, et al.
STAR Protoc
. 2021 Jun;
2(2):100561.
PMID: 34095869
Here, we describe a protocol combining functional metrics with genomic data to elucidate drivers of within-cell-type heterogeneity via the phenotype-to-genotype link. This technique involves using fluorescence tagging to label and...
25.
Benitez J, Finlay D, Castanza A, Parisian A, Ma J, Longobardi C, et al.
Neuro Oncol
. 2021 Jan;
23(7):1072-1086.
PMID: 33428749
Background: Glioblastoma (GBM) is the most common primary brain tumor in adults with a median survival of approximately 15 months; therefore, more effective treatment options for GBM are required. To...
26.
Rusert J, Juarez E, Brabetz S, Jensen J, Garancher A, Chau L, et al.
Cancer Res
. 2020 Oct;
80(23):5393-5407.
PMID: 33046443
Medulloblastoma is among the most common malignant brain tumors in children. Recent studies have identified at least four subgroups of the disease that differ in terms of molecular characteristics and...
27.
Gevaert O, Nabian M, Bakr S, Everaert C, Shinde J, Manukyan A, et al.
JCO Clin Cancer Inform
. 2020 May;
4:421-435.
PMID: 32383980
Purpose: The availability of increasing volumes of multiomics, imaging, and clinical data in complex diseases such as cancer opens opportunities for the formulation and development of computational imaging genomics methods...
28.
Banerjee S, Wei T, Wang J, Lee J, Gutierrez H, Chapman O, et al.
Proc Natl Acad Sci U S A
. 2019 Nov;
116(49):24881-24891.
PMID: 31754034
Dependence on the 26S proteasome is an Achilles' heel for triple-negative breast cancer (TNBC) and multiple myeloma (MM). The therapeutic proteasome inhibitor, bortezomib, successfully targets MM but often leads to...
29.
Tokita M, Nahas S, Briggs B, Malicki D, Mesirov J, Reyes I, et al.
Cold Spring Harb Mol Case Stud
. 2019 Oct;
5(5).
PMID: 31624069
Genome sequencing was performed on matched normal and tumor tissue from a 6.5-yr-old boy with a diagnosis of recurrent medulloblastoma. A pathogenic heterozygous c.432+1G>A canonical splice donor site variant in...
30.
Mah C, Wenzel A, Juarez E, Tabor T, Reich M, Mesirov J
F1000Res
. 2019 Jul;
7:1306.
PMID: 31316748
Single-cell RNA sequencing (scRNA-seq) has emerged as a popular method to profile gene expression at the resolution of individual cells. While there have been methods and software specifically developed to...