Jill P Mesirov
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Explore the profile of Jill P Mesirov including associated specialties, affiliations and a list of published articles.
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128
Citations
82678
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Recent Articles
31.
Mah C, Mesirov J, Chavez L
F1000Res
. 2019 May;
7.
PMID: 31105932
Illumina Infinium DNA methylation arrays are a cost-effective technology to measure DNA methylation at CpG sites genome-wide and across cohorts of normal and cancer samples. While copy number alterations are...
32.
Brenner S, Bulyk M, Crawford D, Mesirov J, Morgan A, Radivojac P
Pac Symp Biocomput
. 2019 Mar;
24:220-223.
PMID: 30864324
For the 2019 Pacific Symposium on Biocomputing's session on precision medicine, we present new research on computational techniques in range of areas including data curation, whole genome analysis, transcriptomics, microbiome...
33.
Krug K, Mertins P, Zhang B, Hornbeck P, Raju R, Ahmad R, et al.
Mol Cell Proteomics
. 2018 Dec;
18(3):576-593.
PMID: 30563849
Signaling pathways are orchestrated by post-translational modifications (PTMs) such as phosphorylation. However, pathway analysis of PTM data sets generated by mass spectrometry (MS)-based proteomics is typically performed at a gene-centric...
34.
Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin A, Kim S, et al.
Nature
. 2018 Dec;
565(7738):E5-E6.
PMID: 30559381
No abstract available.
35.
Archer T, Ehrenberger T, Mundt F, Gold M, Krug K, Mah C, et al.
Cancer Cell
. 2018 Sep;
34(3):396-410.e8.
PMID: 30205044
There is a pressing need to identify therapeutic targets in tumors with low mutation rates such as the malignant pediatric brain tumor medulloblastoma. To address this challenge, we quantitatively profiled...
36.
Robinson J, Turner D, Durand N, Thorvaldsdottir H, Mesirov J, Aiden E
Cell Syst
. 2018 Feb;
6(2):256-258.e1.
PMID: 29428417
Contact mapping experiments such as Hi-C explore how genomes fold in 3D. Here, we introduce Juicebox.js, a cloud-based web application for exploring the resulting datasets. Like the original Juicebox application,...
37.
Hachigian L, Carmona V, Fenster R, Kulicke R, Heilbut A, Sittler A, et al.
Cell Rep
. 2017 Dec;
21(10):2688-2695.
PMID: 29212017
Alteration of corticostriatal glutamatergic function is an early pathophysiological change associated with Huntington's disease (HD). The factors that regulate the maintenance of corticostriatal glutamatergic synapses post-developmentally are not well understood....
38.
Robinson J, Thorvaldsdottir H, Wenger A, Zehir A, Mesirov J
Cancer Res
. 2017 Nov;
77(21):e31-e34.
PMID: 29092934
Manual review of aligned reads for confirmation and interpretation of variant calls is an important step in many variant calling pipelines for next-generation sequencing (NGS) data. Visual inspection can greatly...
39.
Kim J, Abudayyeh O, Yeerna H, Yeang C, Stewart M, Jenkins R, et al.
Cell Syst
. 2017 Aug;
5(2):105-118.e9.
PMID: 28837809
The systematic sequencing of the cancer genome has led to the identification of numerous genetic alterations in cancer. However, a deeper understanding of the functional consequences of these alterations is...
40.
Reich M, Tabor T, Liefeld T, Thorvaldsdottir H, Hill B, Tamayo P, et al.
Cell Syst
. 2017 Aug;
5(2):149-151.e1.
PMID: 28822753
Interactive analysis notebook environments promise to streamline genomics research through interleaving text, multimedia, and executable code into unified, sharable, reproducible "research narratives." However, current notebook systems require programming knowledge, limiting...