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Jian-Ping Lai

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Citations 427
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Recent Articles
1.
Liu Y, Tang X, Zeng Q, Lai J
Sci Rep . 2024 Aug; 14(1):19918. PMID: 39198627
Ultraviolet absorption ability of modifiers is essential to protect asphalt from ageing. However, the detailed correlation between them remains unclear. In this study, zinc oxide nanoparticles were used as modifiers,...
2.
Huang D, Liao M, Tong J, Yuan W, Peng D, Lai J, et al.
Aging (Albany NY) . 2021 Nov; 13(22):24621-24639. PMID: 34799469
Emerging evidence revealed the critical roles of long non-coding RNAs (lncRNAs) in maintaining genomic instability. However, genome instability-associated lncRNAs (GILncRNAs) and their performance in clinical prognostic significance in hepatocellular carcinoma...
3.
Meshki J, Douglas S, Lai J, Schwartz L, Kilpatrick L, Tuluc F
J Biol Chem . 2009 Jan; 284(14):9280-9. PMID: 19179340
We have investigated the effect of neurokinin 1 receptor (NK1R) agonists on HEK293 cells transfected with the NK1R receptor. The NK1R receptor mediates dramatic shape changes that include contractions of...
4.
Douglas S, Lai J, Tuluc F, Schwartz L, Kilpatrick L
Ann N Y Acad Sci . 2008 Dec; 1144:90-6. PMID: 19076368
Substance P (SP) is upregulated in HIV infection in adult men and women, as determined by increased plasma levels. There is a reciprocal and bidirectional relationship between substance P and...
5.
Chernova I, Lai J, Li H, Schwartz L, Tuluc F, Korchak H, et al.
J Leukoc Biol . 2008 Oct; 85(1):154-64. PMID: 18835883
Substance P (SP) is a potent modulator of monocyte/macrophage function. The SP-preferring receptor neurokinin-1 receptor (NK1R) has two forms: a full-length NK1R (NK1R-F) isoform and a truncated NK1R (NK1R-T) isoform,...
6.
Lai J, Huang J
Zhongguo Shi Yan Xue Ye Xue Za Zhi . 2008 Aug; 16(4):777-80. PMID: 18718059
The aim of this study was to investigate the inhibitive effect of artesunate (ART) on CML cell line K562 and its influence on VEGF expression in vitro. Human CML cell...
7.
Lai J, Lai S, Tuluc F, Tansky M, Kilpatrick L, Leeman S, et al.
Proc Natl Acad Sci U S A . 2008 Aug; 105(34):12605-10. PMID: 18713853
The neurokinin-1 receptor (NK1R) has two naturally occurring forms that differ in the length of the carboxyl terminus: a full-length receptor consisting of 407 aa and a truncated receptor consisting...
8.
Douglas S, Lynch K, Lai J
J Neurol Sci . 2008 Jun; 272(1-2):174-7. PMID: 18572194
The neurokinin-1 receptor, a G-protein coupled receptor, is present in cells of the nervous system and the immune system. Utilizing our recently developed SYBR green-based RT-PCR, we quantified full-length and...
9.
Wang X, Douglas S, Lai J, Tuluc F, Tebas P, Ho W
J Neuroimmune Pharmacol . 2007 Nov; 2(1):42-8. PMID: 18040825
Background: Despite the success of antiretroviral therapy in controlling HIV replication, treatment failure may ultimately occur in more than 50% of the individuals on antiretroviral therapy. Cellular targets offer an...
10.
Lai J, Cnaan A, Zhao H, Douglas S
J Neurosci Methods . 2007 Nov; 168(1):127-33. PMID: 18035424
We have applied a newly developed SYBR green-based real-time RT-PCR assay for quantification of full-length and truncated neurokinin-1 receptor (NK1R) mRNA expression in nine regions of human brain tissues obtained...