Laurie E Kilpatrick
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Explore the profile of Laurie E Kilpatrick including associated specialties, affiliations and a list of published articles.
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858
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Recent Articles
1.
Yang Q, Langston J, Prosniak R, Pettigrew S, Zhao H, Perez E, et al.
Front Immunol
. 2024 Mar;
15:1341752.
PMID: 38524125
Purpose: Sepsis is a clinical syndrome defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis is a highly heterogeneous syndrome with distinct phenotypes that impact...
2.
Liu D, Langston J, Prabhakarpandian B, Kiani M, Kilpatrick L
Front Cell Infect Microbiol
. 2024 Jan;
13:1274842.
PMID: 38259971
Sepsis is a global health concern accounting for more than 1 in 5 deaths worldwide. Sepsis is now defined as life-threatening organ dysfunction caused by a dysregulated host response to...
3.
Amoafo E, Entsie P, Albayati S, Dorsam G, Kunapuli S, Kilpatrick L, et al.
Front Immunol
. 2022 Nov;
13:1015577.
PMID: 36405709
Sepsis, a complex clinical syndrome resulting from a serious infection, is a major healthcare problem associated with high mortality. Sex-related differences in the immune response to sepsis have been proposed...
4.
Langston J, Yang Q, Kiani M, Kilpatrick L
Shock
. 2022 Nov;
59(2):224-231.
PMID: 36377365
Sepsis is a major health issue and a leading cause of death in hospitals globally. The treatment of sepsis is largely supportive, and there are no therapeutics available that target...
5.
Corkey B, Kilpatrick L, Evans-Molina C
Diabetes
. 2022 Sep;
71(10):2067-2074.
PMID: 36126206
Several unrelated findings led us to hypothesize that induction of autoimmunity is a consequence of a prior major inflammatory event in individuals with susceptible HLA phenotypes and elevated sensitivity to...
6.
Molecular Framework of Mouse Endothelial Cell Dysfunction during Inflammation: A Proteomics Approach
Rossi M, Langston J, Singh N, Merali C, Yang Q, Merali S, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955534
A key aspect of cytokine-induced changes as observed in sepsis is the dysregulated activation of endothelial cells (ECs), initiating a cascade of inflammatory signaling leading to leukocyte adhesion/migration and organ...
7.
Langston J, Rossi M, Yang Q, Ohley W, Perez E, Kilpatrick L, et al.
Vasc Biol
. 2022 May;
4(1):R15-R34.
PMID: 35515704
During sepsis, defined as life-threatening organ dysfunction due to dysregulated host response to infection, systemic inflammation activates endothelial cells and initiates a multifaceted cascade of pro-inflammatory signaling events, resulting in...
8.
Yang Q, Langston J, Tang Y, Prabhakarpandian B, Kilpatrick L, Kiani M
J Vis Exp
. 2021 Dec;
(178).
PMID: 34958086
Leukocyte-endothelial cell interactions play an important role in inflammatory diseases such as sepsis. During inflammation, excessive migration of activated leukocytes across the vascular endothelium into key organs can lead to...
9.
Yang Q, Wijerathne H, Langston J, Kiani M, Kilpatrick L
Int J Mol Sci
. 2021 Aug;
22(15).
PMID: 34360536
The endothelium is the inner layer of all blood vessels and it regulates hemostasis. It also plays an active role in the regulation of the systemic inflammatory response. Systemic inflammatory...
10.
Sun S, Kilpatrick L, Jensen L
J Invest Dermatol
. 2021 Jul;
142(1):247-251.e2.
PMID: 34280465
No abstract available.