Jessica Schulze
Overview
Explore the profile of Jessica Schulze including associated specialties, affiliations and a list of published articles.
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19
Citations
458
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Recent Articles
11.
Bellmann L, Zelle-Rieser C, Milne P, Resteu A, Tripp C, Hermann-Kleiter N, et al.
J Invest Dermatol
. 2020 Jun;
141(1):84-94.e6.
PMID: 32522485
Langerhans cells (LCs) in the skin are a first line of defense against pathogens but also play an essential role in skin homeostasis. Their exclusive expression of the C-type lectin...
12.
Peteranderl C, Kuznetsova I, Schulze J, Hardt M, Lecuona E, Sznajder J, et al.
Am J Respir Cell Mol Biol
. 2019 Aug;
61(3):395-398.
PMID: 31469298
No abstract available.
13.
Wamhoff E, Schulze J, Bellmann L, Rentzsch M, Bachem G, Fuchsberger F, et al.
ACS Cent Sci
. 2019 May;
5(5):808-820.
PMID: 31139717
Langerhans cells are a subset of dendritic cells residing in the epidermis of the human skin. As such, they are key mediators of immune regulation and have emerged as prime...
14.
Schulze J, Rentzsch M, Kim D, Bellmann L, Stoitzner P, Rademacher C
Biochemistry
. 2019 May;
58(21):2576-2580.
PMID: 31062587
The skin is an attractive site for vaccination and harbors a dense network of Langerhans cells that are the prime target for antigen delivery approaches in the epidermis. While specific...
15.
Schulze J, Baukmann H, Wawrzinek R, Fuchsberger F, Specker E, Aretz J, et al.
ACS Chem Biol
. 2018 Nov;
13(12):3229-3235.
PMID: 30480432
Fragment-based drug discovery is a powerful complement to conventional high-throughput screening, especially for difficult targets. Screening low-molecular-weight fragments usually requires highly sensitive biophysical methods, because of the generally low affinity...
16.
Ng S, Bennett N, Schulze J, Gao N, Rademacher C, Derda R
Bioorg Med Chem
. 2018 Oct;
26(19):5368-5377.
PMID: 30344001
We have employed genetically-encoded fragment-based discovery to identify novel glycopeptides with affinity for the dendritic cell receptor DC-SIGN. Starting from libraries of 10 mannose-conjugated peptides, we identified glycopeptides that exhibited...
17.
Hanske J, Schulze J, Aretz J, McBride R, Loll B, Schmidt H, et al.
J Biol Chem
. 2016 Dec;
292(3):862-871.
PMID: 27903635
The recognition of pathogen surface polysaccharides by glycan-binding proteins is a cornerstone of innate host defense. Many members of the C-type lectin receptor family serve as pattern recognition receptors facilitating...
18.
Schulze J, Moosmayer D, Weiske J, Fernandez-Montalvan A, Herbst C, Jung M, et al.
J Biomol Screen
. 2014 Oct;
20(2):180-9.
PMID: 25266565
Bromodomain protein 4 (BRD4), a member of the bromodomain and extra-terminal (BET) protein family, acts as a central element in transcriptional elongation and plays essential roles in cell proliferation. Inhibition...
19.
Jung M, Philpott M, Muller S, Schulze J, Badock V, Eberspacher U, et al.
J Biol Chem
. 2014 Feb;
289(13):9304-19.
PMID: 24497639
Bromodomain protein 4 (BRD4) is a member of the bromodomain and extra-terminal domain (BET) protein family. It binds to acetylated histone tails via its tandem bromodomains BD1 and BD2 and...