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Jessica Schulze

Explore the profile of Jessica Schulze including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 458
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Recent Articles
1.
Hoffmann T, Michel J, Nitsche A, Mache C, Schulze J, Wolff T, et al.
Sci Data . 2024 Dec; 11(1):1322. PMID: 39632915
Conventional thin section electron microscopy of viral pathogens, such as the pandemic SARS-CoV-2, can provide structural information on the virus particle phenotype and its evolution. We recorded about 900 transmission...
2.
Niemeyer D, Stenzel S, Veith T, Schroeder S, Friedmann K, Weege F, et al.
PLoS Biol . 2022 Nov; 20(11):e3001871. PMID: 36383605
Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) Alpha and Delta are more transmissible, infectious, and pathogenic than previous variants. Phenotypic properties of...
3.
Mache C, Schulze J, Holland G, Bourquain D, Gensch J, Oh D, et al.
Commun Biol . 2022 Oct; 5(1):1138. PMID: 36302956
SARS-CoV-2 and its emerging variants of concern remain a major threat for global health. Here we introduce an infection model based upon polarized human Alveolar Epithelial Lentivirus immortalized (hAELVi) cells...
4.
Honzke K, Obermayer B, Mache C, Fatykhova D, Kessler M, Dokel S, et al.
Eur Respir J . 2022 Jun; 60(6). PMID: 35728978
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilises the angiotensin-converting enzyme 2 (ACE2) transmembrane peptidase as cellular entry receptor. However, whether SARS-CoV-2 in the alveolar compartment is strictly ACE2-dependent...
5.
Grossegesse M, Bourquain D, Neumann M, Schaade L, Schulze J, Mache C, et al.
J Proteome Res . 2022 Jan; 21(2):459-469. PMID: 34982558
Severe acute respiratory syndrome (SARS)-CoV and SARS-CoV-2 infections are characterized by remarkable differences, including infectivity and case fatality rate. The underlying mechanisms are not well understood, illustrating major knowledge gaps...
6.
Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra I, Mittermaier M, et al.
Cell . 2021 Dec; 184(26):6243-6261.e27. PMID: 34914922
COVID-19-induced "acute respiratory distress syndrome" (ARDS) is associated with prolonged respiratory failure and high mortality, but the mechanistic basis of lung injury remains incompletely understood. Here, we analyze pulmonary immune...
7.
Hein S, Herrlein M, Mhedhbi I, Bender D, Haberger V, Benz N, et al.
Allergy . 2021 Nov; 77(7):2080-2089. PMID: 34820854
Background: The mRNA vaccine BNT162b2 (Comirnaty, BioNTech/Pfizer) and the vaccine candidate CVnCoV (Curevac) each encode a stabilized spike protein of SARS-CoV2 as antigen but differ with respect to the nature...
8.
Wawrzinek R, Wamhoff E, Lefebre J, Rentzsch M, Bachem G, Domeniconi G, et al.
J Am Chem Soc . 2021 Nov; 143(45):18977-18988. PMID: 34748320
Dendritic cells (DC) are antigen-presenting cells coordinating the interplay of the innate and the adaptive immune response. The endocytic C-type lectin receptors DC-SIGN and Langerin display expression profiles restricted to...
9.
Rentzsch M, Wawrzinek R, Zelle-Rieser C, Strandt H, Bellmann L, Fuchsberger F, et al.
Front Immunol . 2021 Nov; 12:732298. PMID: 34745102
Immune modulating therapies and vaccines are in high demand, not least to the recent global spread of SARS-CoV2. To achieve efficient activation of the immune system, professional antigen presenting cells...
10.
Schulze J, Mache C, Balazs A, Frey D, Niemeyer D, Olze H, et al.
J Infect Dis . 2021 Oct; 224(12):2020-2024. PMID: 34651643
Background: The upper respiratory tract (URT) is the primary entry site for severe acute respiratory syndrome 2 (SARS-CoV-2) and other respiratory viruses, but its involvement in viral amplification and pathogenesis...