Jerry J Fong
Overview
Explore the profile of Jerry J Fong including associated specialties, affiliations and a list of published articles.
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11
Citations
427
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Recent Articles
1.
Hsu M, Okamura S, De Magalhaes Filho C, Bergeron D, Rodriguez A, West M, et al.
Cancer Immunol Immunother
. 2022 Jul;
72(1):151-168.
PMID: 35776159
The complex immunosuppressive nature of solid tumor microenvironments poses a significant challenge to generating efficacious and durable anticancer responses. Photoimmunotherapy is a cancer treatment strategy by which an antibody is...
2.
Tsai C, Riestra A, Ali S, Fong J, Liu J, Hughes G, et al.
J Innate Immun
. 2019 Dec;
12(4):333-343.
PMID: 31805552
Pathogenic microorganisms are sensed by the inflammasome, resulting in the release of the pro-immune and proinflammatory cytokine interleukin-1β (IL-1β). In humans, the paired <underline>s</underline>ialic acid-binding Ig-like lectin receptors Siglec-5 (inhibitory)...
3.
Landig C, Hazel A, Kellman B, Fong J, Schwarz F, Agarwal S, et al.
Evol Appl
. 2019 Jan;
12(2):337-349.
PMID: 30697344
causes the sexually transmitted disease gonorrhea exclusively in humans and uses multiple strategies to infect, including acquisition of host sialic acids that cap and mask lipooligosaccharide termini, while restricting complement...
4.
Fong J, Tsai C, Saha S, Nizet V, Varki A, Bui J
Proc Natl Acad Sci U S A
. 2018 Sep;
115(41):10410-10415.
PMID: 30254166
Natural killer (NK) cells are innate immune lymphocytes that recognize and destroy abnormal host cells, such as tumor cells or those infected by viral pathogens. To safely accomplish these functions,...
5.
Graustein A, Horne D, Fong J, Schwarz F, Mefford H, Peterson G, et al.
Tuberculosis (Edinb)
. 2017 Apr;
104:38-45.
PMID: 28454648
Humans exposed to Mycobacterium tuberculosis (Mtb) have variable susceptibility to tuberculosis (TB) and its outcomes. Siglec-5 and Siglec-14 are members of the sialic-acid binding lectin family that regulate immune responses...
6.
Fong J, Sreedhara K, Deng L, Varki N, Angata T, Liu Q, et al.
EMBO J
. 2015 Oct;
34(22):2775-88.
PMID: 26459514
The intracellular chaperone heat-shock protein 70 (Hsp70) can be secreted from cells, but its extracellular role is unclear, as the protein has been reported to both activate and suppress the...
7.
Schwarz F, Fong J, Varki A
Adv Exp Med Biol
. 2014 Nov;
842:1-16.
PMID: 25408333
No abstract available.
8.
Ali S, Fong J, Carlin A, Busch T, Linden R, Angata T, et al.
J Exp Med
. 2014 May;
211(6):1231-42.
PMID: 24799499
Group B Streptococcus (GBS) causes invasive infections in human newborns. We recently showed that the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5),...
9.
Fong J, Nguyen B, Bridger R, Medrano E, Wells L, Pan S, et al.
J Biol Chem
. 2012 Feb;
287(15):12195-203.
PMID: 22371497
O-Linked β-N-acetylglucosamine, or O-GlcNAc, is a dynamic post-translational modification that cycles on and off serine and threonine residues of nucleocytoplasmic proteins. The O-GlcNAc modification shares a complex relationship with phosphorylation,...
10.
Dekaney C, Fong J, Rigby R, Lund P, Henning S, Helmrath M
Am J Physiol Gastrointest Liver Physiol
. 2007 Sep;
293(5):G1013-22.
PMID: 17855764
Sustained increases in mucosal surface area occur in remaining bowel following massive intestinal loss. The mechanisms responsible for expanding and perpetuating this response are not presently understood. We hypothesized that...