Jeremy Leipzig
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Explore the profile of Jeremy Leipzig including associated specialties, affiliations and a list of published articles.
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30
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2765
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Recent Articles
11.
Kilbaugh T, Lvova M, Karlsson M, Zhang Z, Leipzig J, Wallace D, et al.
PLoS One
. 2015 Jun;
10(6):e0130927.
PMID: 26098565
Background: Traumatic brain injury (TBI) has been shown to activate the peripheral innate immune system and systemic inflammatory response, possibly through the central release of damage associated molecular patterns (DAMPs)....
12.
Falk M, Shen L, Gonzalez M, Leipzig J, Lott M, Stassen A, et al.
Mol Genet Metab
. 2014 Dec;
114(3):388-96.
PMID: 25542617
Success rates for genomic analyses of highly heterogeneous disorders can be greatly improved if a large cohort of patient data is assembled to enhance collective capabilities for accurate sequence variant...
13.
Navarro-Gomez D, Leipzig J, Shen L, Lott M, Stassen A, Wallace D, et al.
Bioinformatics
. 2014 Dec;
31(8):1310-2.
PMID: 25505086
Motivation: All current mitochondrial haplogroup classification tools require variants to be detected from an alignment with the reference sequence and to be properly named according to the canonical nomenclature standards...
14.
Glessner J, Bick A, Ito K, Homsy J, Rodriguez-Murillo L, Fromer M, et al.
Circ Res
. 2014 Sep;
115(10):884-896.
PMID: 25205790
Rationale: Congenital heart disease (CHD) is among the most common birth defects. Most cases are of unknown pathogenesis. Objective: To determine the contribution of de novo copy number variants (CNVs)...
15.
Zhang Z, Leipzig J, Sasson A, Yu A, Perin J, Xie H, et al.
BMC Bioinformatics
. 2014 Feb;
14 Suppl 11:S3.
PMID: 24564231
Background: High-throughput sequencing (HTS) technologies are spearheading the accelerated development of biomedical research. Processing and summarizing the large amount of data generated by HTS presents a non-trivial challenge to bioinformatics....
16.
Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton J, et al.
Nature
. 2013 May;
498(7453):220-3.
PMID: 23665959
Congenital heart disease (CHD) is the most frequent birth defect, affecting 0.8% of live births. Many cases occur sporadically and impair reproductive fitness, suggesting a role for de novo mutations....
17.
Barrantes I, Leipzig J, Marwan W
Gene Regul Syst Bio
. 2012 Oct;
6:127-37.
PMID: 23071390
Physarum polycephalum is a unicellular eukaryote belonging to the amoebozoa group of organisms. The complex life cycle involves various cell types that differ in morphology, function, and biochemical composition. Sporulation,...
18.
Shi L, Perin J, Leipzig J, Zhang Z, Sullivan K
Gene
. 2011 Aug;
487(1):21-8.
PMID: 21803131
IRF1 is a transcription factor that participates in interferon signaling. Previous studies of IRF1 binding have utilized in vitro assays. We used ChIP-seq in human monocytes to better define the...
19.
Wang G, Garrigue A, Ciuffi A, Ronen K, Leipzig J, Berry C, et al.
Nucleic Acids Res
. 2008 Apr;
36(9):e49.
PMID: 18411205
Gene transfer has been used to correct inherited immunodeficiencies, but in several patients integration of therapeutic retroviral vectors activated proto-oncogenes and caused leukemia. Here, we describe improved methods for characterizing...
20.
Meekings K, Leipzig J, Bushman F, Taylor G, Bangham C
PLoS Pathog
. 2008 Mar;
4(3):e1000027.
PMID: 18369476
Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in approximately 5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people,...