Jeffrey W Schertzer
Overview
Explore the profile of Jeffrey W Schertzer including associated specialties, affiliations and a list of published articles.
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28
Citations
721
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Recent Articles
1.
Fernandes S, Ortega H, Vaillancourt M, Galdino A, Stotland A, Mun K, et al.
Res Sq
. 2024 Nov;
PMID: 39606469
Antibiotic resistance is one of the most pressing threats to human health, yet recent work highlights how loss of resistance may also drive pathogenesis in some bacteria. In two recent...
2.
Xu Q, Kang D, Meyer M, Pennington C, Gopal C, Schertzer J, et al.
Infect Immun
. 2024 Feb;
92(3):e0040723.
PMID: 38391248
is an opportunistic human pathogen that has developed multi- or even pan-drug resistance toward most frontline and last resort antibiotics, leading to increasing frequency of infections and deaths among hospitalized...
3.
Mathur S, Erickson S, Goldberg L, Hills S, Radin A, Schertzer J
bioRxiv
. 2023 Nov;
PMID: 37986865
Bacterial Outer Membrane Vesicles (OMVs) contribute to virulence, competition, immune avoidance and communication. This has led to great interest in how they are formed. To date, investigation has focused almost...
4.
Xu Q, Kang D, Meyer M, Pennington C, Gopal C, Schertzer J, et al.
bioRxiv
. 2023 Oct;
PMID: 37873290
is an opportunistic human pathogen that has developed multi- or even pan-drug resistance towards most frontline and last resort antibiotics, leading to increasing infections and deaths among hospitalized patients, especially...
5.
Pirhadi E, Vanegas J, Farin M, Schertzer J, Yong X
J Chem Theory Comput
. 2022 Dec;
19(1):363-372.
PMID: 36579901
Biological membranes are fundamental components of living organisms that play an undeniable role in their survival. Molecular dynamics (MD) serves as an essential computational tool for studying biomembranes on molecular...
6.
Maktabi S, Malmstadt N, Schertzer J, Chiarot P
Biomicrofluidics
. 2021 Apr;
15(2):024112.
PMID: 33912267
We present a microfluidic technique that generates asymmetric giant unilamellar vesicles (GUVs) in the size range of 2-14 m. In our method, we (i) create water-in-oil emulsions as the precursors...
7.
Cooke A, Florez C, Dunshee E, Lieber A, Terry M, Light C, et al.
mSphere
. 2020 Nov;
5(6).
PMID: 33239369
Bacterial biofilms are major contributors to chronic infections in humans. Because they are recalcitrant to conventional therapy, they present a particularly difficult treatment challenge. Identifying factors involved in biofilm development...
8.
Maktabi S, Schertzer J, Chiarot P
Soft Matter
. 2019 Apr;
15(19):3938-3948.
PMID: 31011738
The double-membrane cellular envelope of Gram-negative bacteria enables them to endure harsh environments and represents a barrier to many clinically available antibiotics. The outer membrane (OM) is exposed to the...
9.
Cooke A, Nello A, Ernst R, Schertzer J
PLoS One
. 2019 Feb;
14(2):e0212275.
PMID: 30763382
Outer Membrane Vesicles (OMVs) are ubiquitous in bacterial environments and enable interactions within and between species. OMVs are observed in lab-grown and environmental biofilms, but our understanding of their function...
10.
Li A, Schertzer J, Yong X
J Biol Chem
. 2018 Dec;
294(4):1089-1094.
PMID: 30563840
Gram-negative bacteria produce outer-membrane vesicles (OMVs) that package genetic elements, virulence factors, and cell-to-cell communication signaling compounds. Despite their importance in many disease-related processes, how these versatile structures are formed...