Jeffrey W Schertzer
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Explore the profile of Jeffrey W Schertzer including associated specialties, affiliations and a list of published articles.
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28
Citations
721
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Recent Articles
11.
Chandler C, Horspool A, Hill P, Wozniak D, Schertzer J, Rasko D, et al.
J Bacteriol
. 2018 Dec;
201(5).
PMID: 30530517
is an opportunistic pathogen found ubiquitously in the environment and commonly associated with airway infection in patients with cystic fibrosis. strain PAO1 is one of the most commonly used laboratory-adapted...
12.
Li A, Schertzer J, Yong X
Phys Chem Chem Phys
. 2018 Sep;
20(36):23635-23648.
PMID: 30191217
Pseudomonas aeruginosa is a common Gram-negative bacterium and opportunistic human pathogen. The distinctive structure of its outer membrane (OM) and outer membrane vesicles (OMVs) plays a fundamental role in bacterial...
13.
Horspool A, Schertzer J
Sci Rep
. 2018 Jul;
8(1):9873.
PMID: 29959355
Delivery of cargo to target cells is fundamental to bacterial competitiveness. One important but poorly understood system, ubiquitous among Gram-negative organisms, involves packaging cargo into outer membrane vesicles (OMVs). These...
14.
Florez C, Raab J, Cooke A, Schertzer J
mBio
. 2017 Aug;
8(4).
PMID: 28790210
The quinolone signal (PQS) is an important quorum-sensing molecule in that also mediates its own packaging and transport by stimulating outer membrane vesicle (OMV) formation. Because OMVs have been implicated...
15.
Lu L, Doak W, Schertzer J, Chiarot P
Soft Matter
. 2016 Oct;
12(36):7521-7528.
PMID: 27722472
Synthetic lipid vesicles have served as important model systems to study cellular membrane biology. Research has shown that the mechanical properties of bilayer membranes significantly affects their biological behavior. The...
16.
Pardo Y, Florez C, Baker K, Schertzer J, Mahler G
FEMS Microbiol Lett
. 2015 Sep;
362(20).
PMID: 26363014
It has been well established that many species of Gram-negative bacteria release nanoscale outer membrane vesicles (OMVs) during normal growth. Furthermore, the roles of these structures in heterotrophic bacteria have...
17.
Lu L, Schertzer J, Chiarot P
Lab Chip
. 2015 Jul;
15(17):3591-9.
PMID: 26220822
We report on a novel microfluidic strategy for the continuous fabrication of monodisperse asymmetric vesicles with customized membrane composition, size, and luminal content. The microfluidic device encompasses a triangular post...
18.
Schertzer J, Whiteley M
J Mol Microbiol Biotechnol
. 2013 Apr;
23(1-2):118-30.
PMID: 23615200
Vesicular transport is a central process in eukaryotes that was believed to be absent in bacteria. However, as our understanding of the communal and interactive lifestyles of bacteria has increased...
19.
Schertzer J, Whiteley M
mBio
. 2012 Mar;
3(2).
PMID: 22415005
Unlabelled: Gram-negative bacteria naturally produce outer membrane vesicles (OMVs) that arise through bulging and pinching off of the outer membrane. OMVs have several biological functions for bacteria, most notably as...
20.
Schertzer J, Whiteley M
Cell
. 2011 Feb;
144(4):469-70.
PMID: 21335231
Exchange of information is critical for bacterial social behaviors. Now Dubey and Ben-Yehuda (2011) provide evidence for bacterial "nanotube" conduits that allow microbes to directly exchange cytoplasmic factors. Protein and...