Jeffrey Neighbors
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Explore the profile of Jeffrey Neighbors including associated specialties, affiliations and a list of published articles.
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5
Citations
14
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Recent Articles
1.
Ren Y, Weeks J, Xue T, Rainbolt J, Bentley K, Shu Y, et al.
Bone Res
. 2023 Oct;
11(1):51.
PMID: 37848449
Eradication of MRSA osteomyelitis requires elimination of distinct biofilms. To overcome this, we developed bisphosphonate-conjugated sitafloxacin (BCS, BV600072) and hydroxybisphosphonate-conjugate sitafloxacin (HBCS, BV63072), which achieve "target-and-release" drug delivery proximal to...
2.
Xie C, Ren Y, Weeks J, Xue T, Rainbolt J, Bentley K, et al.
Res Sq
. 2023 May;
PMID: 37214929
Eradication of MRSA osteomyelitis requires elimination of distinct biofilms. To overcome this, we developed bisphosphonate-conjugated sitafloxacin (BCS, BV600072) and hydroxybisphosphonate-conjugate sitafloxacin (HBCS, BV63072), which achieve "target-and-release" drug delivery proximal to...
3.
Sedghizadeh P, Cherian P, Roshandel S, Tjokro N, Chen C, Junka A, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768310
Osteomyelitis is a limb- and life-threatening orthopedic infection predominantly caused by biofilms. Bone infections are extremely challenging to treat clinically. Therefore, we have been designing, synthesizing, and testing novel antibiotic...
4.
Bhanja D, Neighbors J, Connor J, Zadeh G, Mansouri A
Neurosurgery
. 2022 Jul;
91(4):658-665.
PMID: 35861778
Background: Glioblastoma (GBM) is the most common malignant primary brain tumor with a universally poor prognosis. GBMs express elevated levels of hexokinase 2 (HK2), catalyzing the critical step in glycolysis...
5.
Ren Y, Xue T, Rainbolt J, Bentley K, Galloway C, Liu Y, et al.
Front Cell Infect Microbiol
. 2022 Jul;
12:910970.
PMID: 35811672
infection of bone is difficult to eradicate due to its ability to colonize the osteocyte-lacuno-canalicular network (OLCN), rendering it resistant to standard-of-care (SOC) antibiotics. To overcome this, we proposed two...