Edward M Schwarz
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Explore the profile of Edward M Schwarz including associated specialties, affiliations and a list of published articles.
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323
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10371
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Recent Articles
1.
Saito M, McDonald K, Grier A, Grier A, Meghwani H, Rangel-Moreno J, et al.
bioRxiv
. 2025 Jan;
PMID: 39803468
prosthetic joint infections (PJIs) are broadly considered incurable, and clinical diagnostics that guide conservative vs. aggressive surgical treatments don't exist. Multi-omics studies in a humanized NSG-SGM3 BLT mouse model demonstrate...
2.
Zhou H, Ren Y, Zou K, Jin Y, Liu H, Jiang H, et al.
Adv Healthc Mater
. 2024 Nov;
14(3):e2403261.
PMID: 39604325
Implant-associated Staphylococcus aureus (S. aureus) osteomyelitis (IASO) leads to high orthopedic implant failure rates due to the formation of Staphylococcal abscess community within the bone marrow and bacterial colonization in...
3.
Kuhn E, Sominsky L, Chitto M, Schwarz E, Moriarty T
Pharmaceuticals (Basel)
. 2024 Nov;
17(11).
PMID: 39598446
Sitafloxacin is a 4th generation fluoroquinolone antibiotic with broad activity against a wide range of Gram-negative and Gram-positive bacteria. It is approved in Japan and used to treat pneumonia and...
4.
Kates S, Owen J, Xie C, Ren Y, Muthukrishnan G, Schwarz E
Injury
. 2024 Oct;
55 Suppl 6:111631.
PMID: 39482036
Although vaccines have been hailed as one of the greatest advances in medicine based on their unparalleled cost-effectiveness in eradicating life-threatening infectious diseases, their role in orthopedic trauma-related infections is...
5.
Bell R, Brendel M, Konnaris M, Xiang J, Otero M, Fontana M, et al.
Nat Commun
. 2024 Aug;
15(1):7503.
PMID: 39209814
Rheumatoid arthritis (RA) is a complex immune-mediated inflammatory disorder in which patients suffer from inflammatory-erosive arthritis. Recent advances on histopathology heterogeneity of RA synovial tissue revealed three distinct phenotypes based...
6.
Kenney H, Chen K, Schnur L, Fox J, Wood R, Xing L, et al.
PLoS One
. 2024 Jul;
19(7):e0305623.
PMID: 38968295
Background: Development of reliable disease activity biomarkers is critical for diagnostics, prognostics, and novel drug development. Although computed tomography (CT) is the gold-standard for quantification of bone erosions, there are...
7.
Lekkala S, Ren Y, Weeks J, Lee K, Tay A, Liu B, et al.
PLoS One
. 2024 Jun;
19(6):e0296140.
PMID: 38900759
Implant-associated osteomyelitis remains a major orthopaedic problem. As neutrophil swarming to the surgical site is a critical host response to prevent infection, visualization and quantification of this dynamic behavior at...
8.
Maloney M, Haddas R, Schwarz E, Nelms S, Rizzone K
Clin Sports Med
. 2024 Feb;
43(2):271-277.
PMID: 38383109
Although the twenty-first century has seen major advances in evidence-based medicine to improve health, athletic performance, and injury prevention, our inability to implement these best practices across underserved American communities...
9.
Sechrist Z, Lee G, Schwarz E, Cole C
PLoS One
. 2024 Jan;
19(1):e0292196.
PMID: 38165848
Noninvasive imaging is central to preclinical, in vivo models of pancreatic ductal adenocarcinoma (PDAC). While bioluminescent imaging (BLI) is a gold standard, its signal is dependent on the metabolic activity...
10.
Peng Y, Kenney H, Bentley K, Xing L, Ritchlin C, Schwarz E
Front Immunol
. 2023 Dec;
14:1275871.
PMID: 38155962
Objective: Inflammatory-erosive arthritis is exacerbated by dysfunction of joint-draining popliteal lymphatic vessels (PLVs). Synovial mast cells are known to be pro-inflammatory in rheumatoid arthritis (RA). In other settings they have...