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Jeffrey B Cheng

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Articles 34
Citations 1382
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Recent Articles
1.
Taylor M, Yuan M, Wang S, North J, Cheng J, Cheng J, et al.
Br J Dermatol . 2024 Nov; PMID: 39499646
No abstract available.
2.
Wu Z, Kondo A, McGrady M, Baker E, Chidester B, Wu E, et al.
Cell Rep Methods . 2024 Aug; 4(8):100838. PMID: 39127044
Tissues are organized into anatomical and functional units at different scales. New technologies for high-dimensional molecular profiling in situ have enabled the characterization of structure-function relationships in increasing molecular detail....
3.
Reinstein Z, Zhang Y, Ospina O, Nichols M, Chu V, Pulido A, et al.
Cancer Discov . 2024 Jul; 14(9):1631-1652. PMID: 39058036
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer with a ∼50% response rate to immune checkpoint blockade (ICB) therapy. To identify predictive biomarkers, we integrated bulk and single-cell...
4.
Xiao T, Eze U, Charruyer-Reinwald A, Weisenberger T, Khalifa A, Abegaze B, et al.
Stem Cell Res Ther . 2024 Mar; 15(1):76. PMID: 38475896
Background: A traditional view is that stem cells (SCs) divide slowly. Meanwhile, both embryonic and pluripotent SCs display a shorter cell cycle duration (CCD) in comparison to more committed progenitors...
5.
Wu D, Hailer A, Wang S, Yuan M, Chan J, El Kurdi A, et al.
Sci Immunol . 2024 Jan; 9(91):eadi2848. PMID: 38277466
Psoriasis vulgaris and other chronic inflammatory diseases improve markedly with therapeutic blockade of interleukin-23 (IL-23) signaling, but the genetic mechanisms underlying clinical responses remain poorly understood. Using single-cell transcriptomics, we...
6.
Taylor M, El Kurdi A, Hailer A, Wang S, Yuan M, Mukhopadhyay S, et al.
J Invest Dermatol . 2023 Oct; 144(4):898-901.e3. PMID: 37879399
No abstract available.
7.
Yu D, Zhao J, Lee E, Kim D, Mahapatra R, Rose E, et al.
J Clin Invest . 2023 Sep; 133(21). PMID: 37721853
The facilitative GLUT1 and GLUT3 hexose transporters are expressed abundantly in macrophages, but whether they have distinct functions remains unclear. We confirmed that GLUT1 expression increased after M1 polarization stimuli...
8.
Hailer A, Wu D, El Kurdi A, Yuan M, Cho R, Cheng J
STAR Protoc . 2023 Apr; 4(2):102239. PMID: 37120815
Single-cell RNA sequencing (scRNA-seq) allows for high-resolution analysis of transcriptionally dysregulated cell subpopulations in inflammatory diseases. However, it can be challenging to properly isolate viable immune cells from human skin...
9.
Hakimi M, North J, Taylor M, Hailer A, Liu Y, Kim E, et al.
Lancet . 2023 Apr; 401(10385):1381. PMID: 37087172
No abstract available.
10.
Garrison Z, Chang M, Hornick N, Yu W, Cheng J, Kulkarni R
Cancers (Basel) . 2022 Nov; 14(21). PMID: 36358824
Immune related adverse events (irAEs) are one of the leading causes of discontinuation of cancer immunotherapy treatment. Despite extensive research into the frequency and types of irAEs, little is known...