Jean Y H Yang
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Explore the profile of Jean Y H Yang including associated specialties, affiliations and a list of published articles.
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62
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7874
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Recent Articles
11.
Zhu D, Vernon S, DAgostino Z, Wu J, Giles C, Chan A, et al.
Biomolecules
. 2023 Jun;
13(6).
PMID: 37371497
The current coronary artery disease (CAD) risk scores for predicting future cardiovascular events rely on well-recognized traditional cardiovascular risk factors derived from a population level but often fail individuals, with...
12.
Lin Y, Wu T, Chen X, Wan S, Chao B, Xin J, et al.
bioRxiv
. 2023 Jun;
PMID: 37292801
Single-cell technologies offer unprecedented opportunities to dissect gene regulatory mechanisms in context-specific ways. Although there are computational methods for extracting gene regulatory relationships from scRNA-seq and scATAC-seq data, the data...
13.
Chan A, Wu S, Vernon S, Tang O, Figtree G, Liu T, et al.
iScience
. 2023 May;
26(5):106633.
PMID: 37192969
Cardiovascular disease remains a leading cause of mortality with an estimated half a billion people affected in 2019. However, detecting signals between specific pathophysiology and coronary plaque phenotypes using complex...
14.
Xu X, Lubomski M, Holmes A, Sue C, Davis R, Muller S, et al.
Microbiome
. 2023 Mar;
11(1):51.
PMID: 36918961
Background: Unrevealing the interplay between diet, the microbiome, and the health state could enable the design of personalized intervention strategies and improve the health and well-being of individuals. A common...
15.
Hao J, Zou J, Zhang J, Chen K, Wu D, Cao W, et al.
Brief Bioinform
. 2023 Feb;
24(2).
PMID: 36813563
Cell-state transition can reveal additional information from single-cell ribonucleic acid (RNA)-sequencing data in time-resolved biological phenomena. However, most of the current methods are based on the time derivative of the...
16.
Fu X, Patrick E, Yang J, Feng D, Kim J
Comput Biol Med
. 2023 Feb;
154:106576.
PMID: 36736097
The spatial architecture of the tumour microenvironment and phenotypic heterogeneity of tumour cells have been shown to be associated with cancer prognosis and clinical outcomes, including survival. Recent advances in...
17.
Satgunaseelan L, Strbenac D, Tadi S, Nguyen K, Wykes J, Palme C, et al.
Cancers (Basel)
. 2022 Nov;
14(21).
PMID: 36358632
Viruses are well known drivers of several human malignancies. A causative factor for oral cavity squamous cell carcinoma (OSCC) in patients with limited exposure to traditional risk factors, including tobacco...
18.
Lin Y, Loo L, Tran A, Lin D, Moreno C, Hesselson D, et al.
PLoS Comput Biol
. 2022 Oct;
18(10):e1010495.
PMID: 36197936
COVID-19 patients display a wide range of disease severity, ranging from asymptomatic to critical symptoms with high mortality risk. Our ability to understand the interaction of SARS-CoV-2 infected cells within...
19.
Zhang Y, Wong G, Mann G, Muller S, Yang J
Gigascience
. 2022 Jul;
11.
PMID: 35906887
Survival analysis is a branch of statistics that deals with both the tracking of time and the survival status simultaneously as the dependent response. Current comparisons of survival model performance...
20.
Wang K, Pupo G, Tembe V, Patrick E, Strbenac D, Schramm S, et al.
NPJ Digit Med
. 2022 Jul;
5(1):85.
PMID: 35788693
In this modern era of precision medicine, molecular signatures identified from advanced omics technologies hold great promise to better guide clinical decisions. However, current approaches are often location-specific due to...